"The U.S. Food and Drug Administration today approved the VenaSeal closure system (VenaSeal system) to permanently treat varicose veins of the legs by sealing the affected superficial veins using an adhesive agent.
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ZYDERM collagen implant must not be used in patients with severe allergies manifested by a history of anaphylaxis, or history or presence of multiple severe allergies.
ZYDERM collagen implant contains lidocaine and must not be used in patients with known lidocaine hypersensitivity.
ZYDERM collagen implant must not be used in patients with a history of allergies to any bovine collagen product, including but not limited to collagen injectables, collagen implants, hemostatic sponges and collagen- based sutures, because these patients are likely to have hypersensitivity to ZYDERM collagen implant.
ZYDERM collagen implant must not be used in patients undergoing or planning to undergo desensitization injections to meat products, as these injections can contain bovine collagen.
Last reviewed on RxList: 7/5/2013
This monograph has been modified to include the generic and brand name in many instances.
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