Zyloprim (Allopurinol) Drug Information: Description, User Reviews, Drug Side Effects, Interactions

Pill Identifier Search

May 26, 2012

Zyloprim

Gout »

What is gout? What is hyperuricemia?

Gout is a disease that results from an overload of uric acid in the body. This overload of uric acid leads to the formation of tiny crystals of urate that deposit in tissues of the body, especially the joints. When crystals form in the joints, it causes recurring attacks of joint inflammation (arthritis). Gout is considered a chronic and progressive disease. Chronic gout can also lead to deposits of hard lumps of uric acid in the tissues, particularly in and around the joints and may cause joint destruction, decreased kidney function, and kidney stones (nephrolithiasis).

Gout has the unique distinction of being one of the most frequently recorded medical illnesses throughout history. It is often related to an inherited abnormality in the body's ability to process uric acid. Uric acid is a breakdown product of purines that are part of many foods we eat. An abnormality in handling uric acid can cause attacks of p...

Read the Gout article »

« Previous
1
2
3
4
5
6
7
8
9
10
11
12
13
Next »

Zyloprim User Reviews >>

Zyloprim

Take the Gout Quiz

Gout Overview Slideshow Pictures

Rheumatoid Arthritis Slideshow Pictures

font size

ZYLOPRIM®
(allopurinol) 100-mg Scored Tablets and 300-mg Scored Tablets

DRUG DESCRIPTION

ZYLOPRIM (allopurinol) has the following structural formula:

ZYLOPRIM (allopurinol) structural formula illustration

ZYLOPRIM (allopurinol) is known chemically as 1,5-dihydro-4H-pyrazolo [3,4-d]pyrimidin-4-one. It is a xanthine oxidase inhibitor which is administered orally. Each scored white tablet contains 100 mg allopurinol and the inactive ingredients lactose, magnesium stearate, potato starch, and povidone. Each scored peach tablet contains 300 mg allopurinol and the inactive ingredients corn starch, FD&C Yellow No. 6 Lake, lactose, magnesium stearate, and povidone. Its solubility in water at 37°C is 80.0 mg/dL and is greater in an alkaline solution.

What are the possible side effects of allopurinol (Zyloprim)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using allopurinol and call your doctor at once if you have any of these serious side effects:

the first sign of any skin rash, no matter how mild;
pain or bleeding when you urinate;
urinating less than usual or not at all;
fever, sore throat, and headache with a severe blistering, peeling, and red skin rash;

Read All Potential Side Effects and See Pictures of Zyloprim »

What are the precautions when taking allopurinol (Zyloprim)?

Before taking allopurinol, tell your doctor or pharmacist if you are allergic to it; or if you have had a severe reaction to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: liver disease, kidney disease, diabetes, high blood pressure (hypertension), unusual diets (e.g., fasting).

This drug may make you drowsy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely.

Alcohol may decrease the effectiveness of this drug. Limit alcoholic beverages.

Kidney...

Read All Potential Precautions of Zyloprim »

Last reviewed on RxList: 10/11/2010
This monograph has been modified to include the generic and brand name in many instances.