Zymar (Gatifloxacin Ophthalmic Solution) Drug Information: Description, User Reviews, Drug Side Effects, Interactions

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May 26, 2012

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Zymar

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ZYMAR®
(gatifloxacin ophthalmic solution) 0.3%
sterile

DRUG DESCRIPTION

ZYMAR® (gatifloxacin ophthalmic solution) 0.3% is a sterile ophthalmic solution. It is an 8-methoxy fluoroquinolone anti-infective for topical ophthalmic use.

Structure and Empirical Formula:

ZYMAR® (gatifloxacin ophthalmic solution) structural formula illustration

C₁₉H₂₂FN₃O₄ • 1.5 H₂O Mol Wt 402.42

Chemical Name: (±)-1-cyclopropyl-6-fluoro-1, 4-dihydro-8-methoxy-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid sesquihydrate

Contains:

Active: gatifloxacin 0.3% (3 mg/mL).

Preservative: benzalkonium chloride 0.005%.

Inactives: edetate disodium; purified water and sodium chloride. May contain hydrochloric acid and/or sodium hydroxide to adjust pH to approximately 6.

ZYMAR® (gatifloxacin ophthalmic solution) is a sterile, clear, pale yellow colored isotonic unbuffered solution. It has an osmolality of 260-330 mOsm/kg.

What are the possible side effects of gatifloxacin ophthalmic (Zymar)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; slow heart rate, weak pulse, fainting; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have a serious side effect such as:

severe swelling, burning, redness, or discomfort in or around your eye;
eye pain, vision changes, increased sensitivity of your eyes to light;
signs of new infection, such as drainage, crusting, or oozing of your eyes or...

Read All Potential Side Effects and See Pictures of Zymar »

What are the precautions when taking gatifloxacin ophthalmic solution (Zymar)?

Before using this medication, tell your doctor or pharmacist if you are allergic to it; or to quinolone antibiotics (such as ciprofloxacin); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: contact lens use.

Your vision may be temporarily blurred or unstable after applying this drug. Do not drive, use machinery, or do any activity that requires clear vision until you are sure you can perform such activities safely.

Use of this medication for prolonged or repeated periods may result in a secondary infection.

This drug should be used...

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Last reviewed on RxList: 8/14/2007
This monograph has been modified to include the generic and brand name in many instances.