March 23, 2017


(gatifloxacin ophthalmic solution) 0.3%


ZYMAR® (gatifloxacin ophthalmic solution) 0.3% is a sterile ophthalmic solution. It is an 8-methoxy fluoroquinolone anti-infective for topical ophthalmic use.

Structure and Empirical Formula:

ZYMAR® (gatifloxacin ophthalmic solution) structural formula illustration

C19H22FN3O4 • 1.5 H2O                       Mol Wt 402.42

Chemical Name: (±)-1-cyclopropyl-6-fluoro-1, 4-dihydro-8-methoxy-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid sesquihydrate


Active: gatifloxacin 0.3% (3 mg/mL).

Preservative: benzalkonium chloride 0.005%.

Inactives: edetate disodium; purified water and sodium chloride. May contain hydrochloric acid and/or sodium hydroxide to adjust pH to approximately 6.

ZYMAR® (gatifloxacin ophthalmic solution) is a sterile, clear, pale yellow colored isotonic unbuffered solution. It has an osmolality of 260-330 mOsm/kg.

What are the possible side effects of gatifloxacin ophthalmic (Zymar, Zymaxid)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; slow heart rate, weak pulse, fainting; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have a serious side effect such as:

  • severe swelling, burning, redness, or discomfort in or around your eye;
  • eye pain, vision changes, increased sensitivity of your eyes to light;
  • signs of new infection, such as drainage, crusting, or oozing of your eyes or eyelids; or
  • the first sign of any skin...

Read All Potential Side Effects and See Pictures of Zymar »

What are the precautions when taking gatifloxacin ophthalmic solution (Zymar)?

Before using this medication, tell your doctor or pharmacist if you are allergic to it; or to quinolone antibiotics (such as ciprofloxacin); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: contact lens use.

Your vision may be temporarily blurred or unstable after applying this drug. Do not drive, use machinery, or do any activity that requires clear vision until you are sure you can perform such activities safely.

Use of this medication for prolonged or repeated periods may result in a secondary infection.

This drug should be used...

Read All Potential Precautions of Zymar »

Last reviewed on RxList: 8/14/2007
This monograph has been modified to include the generic and brand name in many instances.

Zymar - User Reviews

Zymar User Reviews

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Here is a collection of user reviews for the medication Zymar sorted by most helpful. Patient Discussions FAQs

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