(gatifloxacin) Ophthalmic Solution 0.3% for Topical Ophthalmic Use
ZYMAR® is a quinolone antimicrobial topical ophthalmic solution for the treatment of bacterial conjunctivitis. Its chemical name is (±)-1-Cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-(3-methyl-1-piperazinyl)-4-oxo-3quinolinecarboxylic acid, sesquihydrate. Its molecular formula is C19H22FN3O4 • 1.5 H2O, and its molecular weight is 402.42. Its chemical structure is:
ZYMAR® is a clear, pale yellow, sterile, preserved aqueous solution with an osmolality of 260-330 mOsm/kg and a pH of approximately 6.
ZYMAR® contains the active ingredient gatifloxacin 0.3% (3 mg/mL) and the inactive ingredients benzalkonium chloride 0.005%, edetate disodium, purified water and sodium chloride. ZYMAR® may contain hydrochloric acid and/or sodium hydroxide to adjust pH.
What are the possible side effects of gatifloxacin ophthalmic (Zymar, Zymaxid)?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; slow heart rate, weak pulse, fainting; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have a serious side effect such as:
- severe swelling, burning, redness, or discomfort in or around your eye;
- eye pain, vision changes, increased sensitivity of your eyes to light;
- signs of new infection, such as drainage, crusting, or oozing of your eyes or eyelids; or
- the first sign of any skin...
What are the precautions when taking gatifloxacin ophthalmic solution (Zymar)?
Before using this medication, tell your doctor or pharmacist if you are allergic to it; or to quinolone antibiotics (such as ciprofloxacin); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Before using this medication, tell your doctor or pharmacist your medical history, especially of: contact lens use.
Your vision may be temporarily blurred or unstable after applying this drug. Do not drive, use machinery, or do any activity that requires clear vision until you are sure you can perform such activities safely.
Use of this medication for prolonged or repeated periods may result in a secondary infection.
This drug should be used...
Last reviewed on RxList: 3/31/2017
This monograph has been modified to include the generic and brand name in many instances.
Additional Zymar Information
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