Zymaxid (Gatifloxacin Ophthalmic Solution) Drug Information: Description, User Reviews, Drug Side Effects, Interactions

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May 27, 2012

Zymaxid

Pink Eye »

What is "pink eye"?

Pink eye, or conjunctivitis, is redness and inflammation of the membranes (conjunctiva) covering the whites of the eyes and the membranes on the inner part of the eyelids. These membranes react to a wide range of bacteria, viruses, allergy-provoking agents, irritants, and toxic agents, as well as to underlying diseases within the body. Viral and bacterial forms of conjunctivitis are common in childhood, but they occur in adults as well. Pink eye can occur in people of any age. Overall, however, there are many causes of pink eye. These can be classified as either infectious or noninfectious. Pink eye does not cause any changes in vision.

What infections cause pink eye, what are infectious pink eye symptoms, and how are they treated?

Viral p...

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Zymaxid

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ZYMAXID™
(gatifloxacin) Ophthalmic Solution 0.5%

DRUG DESCRIPTION

ZYMAXID™ (gatifloxacin ophthalmic solution) sterile ophthalmic solution is an 8-methoxyfluoroquinolone anti-infective for the treatment of bacterial conjunctivitis. Its chemical name is (±)-1-Cyclopropyl-6fluoro-1,4-dihydro-8-methoxy-7-(3-methyl1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid, sesquihydrate. Its molecular formula is C₁₉H₂₂FN₃O₄ • 1½H₂O, and its molecular weight is 402.42. Its chemical structure is:

ZYMAXID™(gatifloxacin) Structural Formula Illustration

ZYMAXID™ (gatifloxacin ophthalmic solution) is a clear, pale yellow, sterile, preserved aqueous solution with an osmolality of 260-330 mOsm/kg and a pH of 5.1-5.7.

ZYMAXID™ contains Active: gatifloxacin 0.5% (5 mg/mL); Inactives: benzalkonium chloride 0.005%; edetate disodium; purified water; and sodium chloride. May contain hydrochloric acid and/or sodium hydroxide to adjust pH.

What are the precautions when taking gatifloxacin ophthalmic solution (Zymaxid )?

Before using this medication, tell your doctor or pharmacist if you are allergic to it; or to quinolone antibiotics (such as ciprofloxacin); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: contact lens use.

Your vision may be temporarily blurred or unstable after applying this drug. Do not drive, use machinery, or do any activity that requires clear vision until you are sure you can perform such activities safely.

Use of this medication for prolonged or repeated periods may result in a secondary infection.

This drug should be used...

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Last reviewed on RxList: 6/23/2010
This monograph has been modified to include the generic and brand name in many instances.