"The U.S. Food and Drug Administration today expanded the approved use of Zytiga (abiraterone acetate) to treat men with late-stage (metastatic) castration-resistant prostate cancer prior to receiving chemotherapy.
The FDA initially appr"...
- Clinician Information:
Zytiga Patient Information including How Should I Take
In this Article
- What is abiraterone (Zytiga)?
- What are the possible side effects of abiraterone (Zytiga)?
- What is the most important information I should know about abiraterone (Zytiga)?
- What should I discuss with my healthcare provider before taking abiraterone (Zytiga)?
- How should I take abiraterone (Zytiga)?
- What happens if I miss a dose (Zytiga)?
- What happens if I overdose (Zytiga)?
- What should I avoid while taking abiraterone (Zytiga)?
- What other drugs will affect abiraterone (Zytiga)?
- Where can I get more information?
What should I discuss with my healthcare provider before taking abiraterone (Zytiga)?
You should not use abiraterone if you are allergic to it, if you are pregnant, or if you have severe liver disease.
To make sure you can safely take abiraterone, tell your doctor if you have any of these other conditions:
- liver disease;
- low levels of potassium in your blood;
- any type of infection;
- high blood pressure;
- congestive heart failure;
- a history of heart disease, fluid retention, or recent heart attack; or
- a history of problems with your adrenal gland or pituitary gland.
FDA pregnancy category X. Although abiraterone is not for use by women, this medication can harm an unborn baby or cause birth defects. Abiraterone tablets should not be handled by a woman who is pregnant or who may become pregnant. If this cannot be avoided, the woman should wear latex gloves.
While you are taking abiraterone and for at least 1 week after your treatment ends: Use a condom to prevent transfer of this medication to your sexual partner if she is pregnant. Use a condom plus another form of effective birth control if your sexual partner could become pregnant.
It is not known whether abiraterone passes into breast milk or if it could harm a nursing baby. Abiraterone should not be used by a woman who is breast-feeding a baby.
How should I take abiraterone (Zytiga)?
Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.
Abiraterone is usually taken once per day while also taking prednisone two times per day. Follow your doctor's instructions.
Take this medicine with a full glass of water. Swallow the abiraterone tablet whole.
Take abiraterone on an empty stomach. Do not eat anything for at least 2 hours before you take abiraterone and for at least 1 hour after you have taken the medicine.
Do not stop using abiraterone or prednisone without first talking to your doctor. You may need to use less and less prednisone before you stop the medication completely.
Your prednisone dosage needs may change if you have surgery, are ill, or are under stress. Do not change your medication dose or schedule without your doctor's advice.
Your blood pressure will need to be checked often. You will also need regular medical tests to be sure this medication is not causing harmful effects. Visit your doctor regularly.
Store at room temperature away from moisture and heat.
Additional Zytiga Information
- Zytiga Drug Interactions Center: abiraterone oral
- Zytiga Side Effects Center
- Zytiga FDA Approved Prescribing Information including Dosage
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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