April 27, 2017
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Zytiga Patient Information including How Should I Take

What should I discuss with my healthcare provider before taking abiraterone (Zytiga)?

You should not use this medication if you are allergic to abiraterone, if you have severe liver disease, or if you are pregnant.

To make sure abiraterone is safe for you, tell your doctor if you have:

  • liver disease;
  • heart disease, high blood pressure;
  • low levels of potassium in your blood;
  • a history of heart disease, fluid retention, or recent heart attack; or
  • a history of problems with your adrenal gland or pituitary gland.

While you are taking abiraterone and for at least 1 week after your treatment ends:

  • If your sexual partner is pregnant--Use a condom to prevent transfer of this medication to her.
  • If your sexual partner could become pregnant--Use a condom plus another form of effective birth control to prevent pregnancy.

FDA pregnancy category X. Although abiraterone is not for use by women, this medication can harm an unborn baby or cause birth defects. Abiraterone tablets should not be handled by a woman who is pregnant or who may become pregnant. If this cannot be avoided, the woman should wear latex gloves.

It is not known whether abiraterone passes into breast milk or if it could harm a nursing baby. Abiraterone should not be used by a woman who is breast-feeding a baby.

How should I take abiraterone (Zytiga)?

Follow all directions on your prescription label. Abiraterone is usually taken once per day while also taking prednisone two times per day. Do not take this medicine in larger or smaller amounts or for longer than recommended.

Your prednisone dosage needs may change if you have surgery, are ill, or are under stress. Do not change your medication dose or schedule without your doctor's advice.

Take this medicine with a full glass of water. Swallow the abiraterone tablet whole.

Take abiraterone on an empty stomach. Do not eat anything for at least 2 hours before you take abiraterone and for at least 1 hour after you have taken the medicine.

Your blood pressure will need to be checked often, and you may need frequent blood tests at your doctor's office.

You should not stop using abiraterone or prednisone suddenly. Follow your doctor's instructions about tapering your prednisone dose.

Store at room temperature away from moisture and heat.

Side Effects Centers

Report Problems to the Food and Drug Administration


You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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