"Dec. 26, 2012 -- Johnnie McKee thought she was out of the woods.
McKee, a 72-year-old grandmother of four from Bethpage, Tenn., was one of nearly 14,000 people who found out this fall that they'd been exposed to tainted medications made by "...
Zyvox Consumer (continued)
Some products that may interact with this drug include: atomoxetine, bethanidine, bupropion, carbamazepine, certain antihistamines (azatadine, carbetapentane, chlorpheniramine), certain eye drops (apraclonidine, brimonidine), herbal products (e.g., ephedra/ma huang, ginseng, tryptophan), indoramin, levodopa, methyldopa, certain narcotic pain relievers (fentanyl, meperidine), papaverine, drugs for Parkinson's disease (such as entacapone, tolcapone), rifampin, sympathomimetics (e.g., ephedrine, methylphenidate), tetrabenazine, other drugs which depress the bone marrow (e.g., cancer chemotherapy).
Avoid taking other MAO inhibitors (isocarboxazid, methylene blue, moclobemide, phenelzine, procarbazine, rasagiline, selegiline, tranylcypromine) within 2 weeks before, during, and after treatment with this medication.
Before taking linezolid, report the use of other drugs that increase serotonin, such as buspirone, dextromethorphan, lithium, St. John's wort, sibutramine, street drugs such as MDMA/"ecstasy," tramadol, tryptophan, "triptans" used to treat migraine headaches (such as eletriptan, sumatriptan), antidepressants (including mirtazapine, trazodone, vilazodone, SSRIs such as citalopram, paroxetine, SNRIs such as duloxetine, venlafaxine, and tricyclics such as amitriptyline, doxepin), among others. The risk of serotonin syndrome may be more likely when you start or increase the dose of these medications.
Check the labels on all your medicines (e.g., cough-and-cold products, diet aids) because they may contain ingredients that could increase your heart rate or blood pressure. Avoid these products while using this medication. Ask your pharmacist for additional information.
Limit your tyramine intake while using this medication and for 2 days after stopping treatment. Also avoid foods or drinks with high tyramine content during use because the combination may cause a serious rise in your blood pressure.
Foods high in tyramine include those that may change as a result of aging, fermentation, pickling, or smoking. The tyramine content of any protein-rich food (meats, fish and dairy products) may increase if stored for long periods or improperly refrigerated. Some foods high in tyramine include aged cheeses (0 to 15 milligrams per ounce); fermented or air-dried meats (0.1 to 8 milligrams per ounce); sauerkraut (8 milligrams per 8 ounces); soy sauce (5 milligrams per 1 teaspoon); tap beers (4 milligrams per 12 ounces); red wines (0 to 6 milligrams per 8 ounces). Total intake of tyramine should be less than 100 milligrams per meal.
Tell your doctor or pharmacist immediately if you notice symptoms of high blood pressure such as fast or pounding heartbeat, vomiting, sweating or headache, chest pain, sudden vision changes, weakness on one side of the body or slurred speech.
Contact your healthcare professional (e.g., doctor, pharmacist or dietician) for more information, including recommendations for your diet.
Although most antibiotics probably do not affect hormonal birth control such as pills, patch, or ring, some antibiotics may decrease their effectiveness. This could cause pregnancy. Examples include rifamycins such as rifampin or rifabutin. Be sure to ask your doctor or pharmacist if you should use additional reliable birth control methods while using this antibiotic.
OVERDOSE: If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly.
NOTES: Your doctor may order eye tests if you are taking this medication for more than 3 months or if you have any vision changes or problems. Keep all medical appointments.
Laboratory and/or medical tests (e.g., CBC, platelets) should be performed periodically to monitor your progress or check for side effects. Consult your doctor for more details.
MISSED DOSE: For the best possible benefit, it is important to receive each scheduled dose of this medication as directed. If you miss a dose, contact your doctor or pharmacist immediately to establish a new dosing schedule. Do not double the dose to catch up.
STORAGE: Consult the product instructions and your pharmacist for storage details. Keep all medications away from children and pets.
Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.
Information last revised October 2011. Copyright(c) 2011 First Databank, Inc.
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