Zyvox (Linezolid) Patient Information: Missed a Dose and What Should I Avoid at RxList

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May 27, 2012

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Staph Infection (Staphylococcus Aureus) »

What is Staphylococcus?

Staphylococcus is a group of bacteria that can cause a number of diseases as a result of infection of various tissues of the body. Staphylococcus is more familiarly known as Staph (pronounced "staff"). Staph-related illness can range from mild and requiring no treatment to severe and potentially fatal.

The name Staphylococcus comes from the Greek staphyle, meaning a bunch of grapes, and kokkos, meaning berry, and that is what Staph bacteria look like under the microscope, like a bunch of grapes or little round berries. (In technical terms, these are gram-positive, facultative anaerobic, usually unencapsulated cocci.)

Over 30 different types of Staphylococci can infect humans, but most infections are caused by Staphylococcus aureus. Staphylococci can be found normally in the nose and on the skin (and less commonly in other locations) of around 25%-30% of healthy adults and...

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Zyvox Patient Information including If I Miss a Dose

What happens if I miss a dose (Zyvox)?

Use the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and use the medicine at your next regularly scheduled time. Do not use extra medicine to make up the missed dose.

What happens if I overdose (Zyvox)?

Seek emergency medical attention if you think you have used too much of this medicine. Overdose may cause weakness, tremors, vomiting, or loss of balance or coordination.

What should I avoid while using linezolid (Zyvox)?

Antibiotic medicines can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or has blood in it, call your doctor. Do not use any medicine to stop the diarrhea unless your doctor has told you to.

While you are using linezolid, avoid taking an "SSRI" antidepressant without telling your doctor. This includes citalopram (Celexa), escitalopram (Lexapro), fluoxetine (Prozac, Sarafem), fluvoxamine (Luvox), paroxetine (Paxil), or sertraline (Zoloft). Taking an SSRI antidepressant together with linezolid can cause symptoms such as anxiety, high fever, sweating, chills or goosebumps, memory problems, trouble concentrating, loss of coordination, or muscle spasms.

Eating tyramine while you are using linezolid can raise your blood pressure to dangerous levels. Avoid foods that have a high level of tyramine, such as:

aged cheeses or meats;
pickled or fermented meats;
smoked or air-dried meats;
sauerkraut;
soy sauce;
tap beer (alcoholic and nonalcoholic);
red wine; or
any meat, cheese, or other protein-based food that has been improperly stored.

You should become very familiar with the list of foods you must avoid while you are using linezolid.

What other drugs will affect linezolid (Zyvox)?

There may be other drugs that can interact with linezolid. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Where can I get more information?

Your pharmacist can provide more information about linezolid.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

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