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Reviewed on 9/17/2019

What other names is 19-nor-dhea known by?

19nor-dehydroepiandrosterone, 19-nor-dehydroepiandrosterone, 19nor-DHEA.

Insufficient Evidence to Rate Effectiveness for...

  • Athletic performance.
  • Other conditions.
More evidence is needed to rate 19-nor-DHEA for this use.

How does 19-nor-dhea work?

After 19-nor-DHEA is taken, the body is thought to change it into other chemicals called hormones. Some of these hormones include chemicals that are similar to testosterone. Testosterone and similar hormones can help build muscle, but can also cause dangerous side effects.

Are there safety concerns?

Special Precautions & Warnings:

Pregnancy and breast-feeding: There is not enough reliable information about the safety of taking 19-nor-DHEA if you are pregnant or breast feeding. Stay on the safe side and avoid use.

Heart disease: 19-nor-DHEA might worsen heart disease in some patients.

Liver problems: 19-nor-DHEA might worsen liver problems in some patients.

There is not enough information available to know if name is safe to take for medical conditions.


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Are there any interactions with medications?

TestosteroneInteraction Rating: Moderate Be cautious with this combination.Talk with your health provider.

19-nor-DHEA might be changed by the body to chemicals similar to testosterone. Taking 19-nor-DHEA along with medications that contain testosterone might increase the chance of side effects including mood changes and heart, kidney, or liver problems.

Dosing considerations for 19-nor-dhea.

The appropriate dose of 19-nor-DHEA depends on several factors such as the user's age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for 19-nor-DHEA. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.

Natural Medicines Comprehensive Database rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, and Insufficient Evidence to Rate (detailed description of each of the ratings).

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19nor-Dehydroepiandrosterone. Available at: Accessed: February 29, 2016.

Granados J, Gillum TL, Christmas KM, et al. Prohormone supplement 3b-hydroxy-5a-androst-1-en-17-one enhances resistance training gains but impairs user health. J Appl Physiol (1985). 2014;116(5):560-9. View abstract.

Joseph JF, Parr MK. Synthetic androgens as designer supplements. Curr Neuropharmacol. 2015;13(1):89-100. View abstract.

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