Medical Editor: John P. Cunha, DO, FACOEP
A-Methapred (methylprednisolone sodium succinate) is an anti-inflammatory steroid used to treat conditions such as arthritis, lupus, dermatitis, Steven's-Johnson Syndrome, asthma, eye inflammation, ulcerative colitis, leukemia, multiple sclerosis, and more. A-Methapred is available in generic form. Common side effects of A-Methapred include:
- muscle weakness
- peptic ulcer
- slow wound healing
- thinning skin
- facial redness
- changes in menstrual cycle
- increased eye pressure
- trouble sleeping
- appetite changes
- increased sweating
- fluid retention
- abdominal bloating
- high blood pressure
- injection site reactions (pain, redness, swelling)
Dosage recommendations for A-Methapred vary for each individual. Talk to your doctor about your individual dosage recommendation. Cyclosporin can interact with A-Methapred. Tell your doctor all medications you are taking. Do not take A-Methapred while getting vaccinated for smallpox. Prolonged use of A-Methapred may cause optic nerve damage, eye infections, or glaucoma. Caution should be exercised if you take A-Methapred while pregnant or breastfeeding.
Our A-Methapred (methylprednisolone sodium succinate) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Fluid and Electrolyte Disturbances
Muscle weakness, Steroid myopathy, Loss of muscle mass, Severe arthralgia, Vertebral compression fractures, Aseptic necrosis of femoral and humeral heads, Pathologic fracture of long bones, Osteoporosis
Development of Cushingoid state, Suppression of growth in children, Secondary adrenocortical and pituitary unresponsiveness, particularly in times of stress, as in trauma, surgery or illness, Menstrual irregularities, Decreased carbohydrate tolerance, Manifestations of latent diabetes mellitus, Increased requirements for insulin or oral hypoglycemic agents in diabetics
The following additional adverse reactions are related to parenteral corticosteroid therapy: Hyperpigmentation or hypopigmentation, Subcutaneous and cutaneous atrophy, Sterile abscess, Anaphylactic reaction with or without circulatory collapse, cardiac arrest, bronchospasm, Urticaria, Nausea and vomiting, Cardiac arrhythmias; hypotension or hypertension
Read the entire FDA prescribing information for A-Methapred (Methylprednisolone Sodium Succinate)