Abilify Antipsychotic for Schizophrenia

Reviewed on 8/15/2022
Generic name: Aripiprazole

Availability: By prescription only

Drug Class: Antipsychotics, 2nd Generation (Atypical Antipsychotics); Antimanic Agents

What Is the Use of Abilify?

Abilify (aripiprazole) is a psychotropic drug (anti-psychotic) that alters brain chemical activity used to treat schizophrenia, mania, depression, bipolar disorders, autistic disorders, and some irritable behavior disorders. Generic Abilify is not available in the U.S., but is available in other countries under the name aripiprazole.

Abilify Oral Tablets, Orally-Disintegrating Tablets, and Oral Solution are prescription medicines used to treat:

  • Schizophrenia
  • Manic or mixed episodes that happen with bipolar I disorder
  • Major depressive disorder (MDD) when ABILIFY is used with antidepressant medicines
  • Irritability associated with autistic disorder
  • Tourette's disorder

Abilify Injection is a prescription medicine used to treat:

  • Agitation associated with schizophrenia or bipolar mania


Schizophrenia is the most disabling mental illness. See Answer

What Are Abilify Side Effects?

Common side effects of Abilify include:

  • dizziness
  • lightheaded
  • drowsiness
  • weakness
  • lightheadedness
  • nausea
  • vomiting
  • stomach upset
  • tiredness
  • excess saliva or drooling
  • choking or trouble swallowing
  • blurred vision
  • headache
  • anxiety
  • weight gain
  • drowsiness
  • sleep problems (insomnia)
  • constipation

Suicidal thoughts are may occur in some patients, especially children, teens, and young adults. Tell your doctor if this occurs.

Other serious side effects of Abilify include:

Seek medical care or call 911 at once if you have the following serious side effects:

  • Severe headache, confusion, slurred speech, arm or leg weakness, trouble walking, loss of coordination, feeling unsteady, very stiff muscles, high fever, profuse sweating, or tremors;
  • Serious eye symptoms such as sudden vision loss, blurred vision, tunnel vision, eye pain or swelling, or seeing halos around lights;
  • Serious heart symptoms include fast, irregular, or pounding heartbeats; fluttering in the chest; shortness of breath; sudden dizziness, lightheartedness, or passing out.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or US national poison hotline at 1-800-222-1222.

Professional Indications: What is Abilify Used to Treat?

Abilify Oral Tablets, Orally-Disintegrating Tablets, and Oral Solution are indicated for the treatment of:

  • Schizophrenia
  • Acute Treatment of Manic and Mixed Episodes associated with Bipolar I Disorder
  • Adjunctive Treatment of Major Depressive Disorder
  • Irritability Associated with Autistic Disorder
  • Treatment of Tourette's Disorder

Abilify Injection is indicated for the treatment of:

  • Agitation associated with schizophrenia or bipolar mania

Read the entire FDA prescribing information for Abilify (aripiprazole).

Patient Usage: How Does Abilify Work In the Body?

Abilify is an antipsychotic medication. It works by changing the actions of chemicals in the brain.

  • Abilify is used to treat the symptoms of psychotic conditions such as schizophrenia and bipolar disorder (manic depression). It is also used together with other medications to treat the major depressive disorder in adults.
  • Abilify is also used to treat irritability and symptoms of aggression, mood swings, temper tantrums, and self-injury related to autistic disorder in children who are at least 6 years old.
  • Abilify may also be used for purposes not listed in this medication guide.
  • Read the entire detailed patient monograph for Abilify (aripiprazole).


Schizophrenia: Symptoms, Types, Causes, Treatment See Slideshow
Medical Editor: John P. Cunha, DO, FACOEP

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