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Acacia

What other names is Acacia known by?

Acacia arabica, Acacia senegal, Acacia verek, Arbre à Gomme Arabique, Bum Senegal, Bomme Arabique, Bomme de Senegal, Bummae Momosae, Goma Arábiga, Gomme Acacia, Gomme Arabique, Gomme d'Acacia, Gomme Sénégal, Gommier Blanc, Gum Acacia, Gum Arabic, Khadir, Kher, Kumatia, Mimosa senegal, Senegalia senegal.

What is Acacia?

Acacia is the gum that is exuded from the acacia tree. It's a dietary fiber that can dissolve in water.

As a medicine, acacia is taken by mouth to reduce cholesterol levels and to help increase weight loss.

In manufacturing, acacia is used as a pharmaceutical ingredient in medications for throat or stomach inflammation and as a film-forming agent in peel-off skin masks.

Don't confuse acacia with sweet acacia (Acacia farnesiana).

Possibly Ineffective for...

  • High cholesterol. Taking acacia by mouth does not seem to lower cholesterol levels.

Insufficient Evidence to Rate Effectiveness for...

  • Dental plaque. Early research suggests that chewing acacia gum for 10 minutes five times daily for 7 days reduces dental plaque more than sugar-free chewing gum.
  • Weight loss. There is early evidence that shows taking 30 grams of powdered acacia daily might help weight loss.
More evidence is needed to rate the effectiveness of acacia for these uses.

QUESTION

Next to red peppers, you can get the most vitamin C from ________________. See Answer

How does Acacia work?

Acacia is a source of dietary fiber. It tends to make people feel full, so they might stop eating earlier than they otherwise would. This might lead to weight loss and reduced cholesterol levels.

Are there safety concerns?

Acacia is LIKELY SAFE for most adults when taken by mouth in amounts commonly found in food.

Acacia is POSSIBLY SAFE when taken by mouth in amounts used for medical purposes. Up to 30 grams daily has been used safely for 6 weeks. However, it can cause minor adverse effects, including gas, bloating, nausea, and loose stools.

Special Precautions & Warnings:

Pregnancy and breast-feeding: Not enough is known about the use of acacia during pregnancy and breast-feeding. Stay on the safe side and avoid use.

Are there any interactions with medications?


Amoxicillin (Amoxil, Trimox)Interaction Rating: Major Do not take this combination.

Acacia can prevent the body from absorbing the antibiotic amoxicillin (Amoxil, Trimox). To prevent this interaction, take acacia at least four hours before or after taking amoxicillin (Amoxil, Trimox).

Dosing considerations for Acacia.

The appropriate dose of acacia depends on several factors such as the user's age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for acacia. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.

Natural Medicines Comprehensive Database rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, and Insufficient Evidence to Rate (detailed description of each of the ratings).

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Reviewed on 9/17/2019
References

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Haridas, V., Arntzen, C. J., and Gutterman, J. U. Avicins, a family of triterpenoid saponins from Acacia victoriae (Bentham), inhibit activation of nuclear factor-kappaB by inhibiting both its nuclear localization and ability to bind DNA. Proc Natl.Acad.Sci U.S.A 9-25-2001;98(20):11557-11562. View abstract.

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Jayatilake, G. S., Freeberg, D. R., Liu, Z., Richheimer, S. L., Blake Nieto, M. E., Bailey, D. T., Haridas, V., and Gutterman, J. U. Isolation and structures of avicins D and G: in vitro tumor-inhibitory saponins derived from Acacia victoriae. J Nat Prod. 2003;66(6):779-783. View abstract.

Joshi, L., Van Eck, J. M., Mayo, K., Di Silvestro, R., Blake Nieto, M. E., Ganapathi, T., Haridas, V., Gutterman, J. U., and Arntzen, C. J. Metabolomics of plant saponins: bioprospecting triterpene glycoside diversity with respect to mammalian cell targets. OMICS. 2002;6(3):235-246. View abstract.

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Sam, C. K., Kesavan, Padmaja, Liam, C. K., Soon, S. C., Lim, A. L., and Ong, E. K. A study of pollen prevalence in relation to pollen allergy in Malaysian asthmatics. Asian Pac.J Allergy Immunol. 1998;16(1):1-4. View abstract.

Shah, B. H., Safdar, B., Virani, S. S., Nawaz, Z., Saeed, S. A., and Gilani, A. H. The antiplatelet aggregatory activity of Acacia nilotica is due to blockade of calcium influx through membrane calcium channels. Gen.Pharmacol 1997;29(2):251-255. View abstract.

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Singh, K. N., Mettal, R. K., and Barthwal, K. C. Hypoglycemia activity of Acacia catechu, Acacia suma, and Albizzia Odoratisima seed diets in normal albino rats. Indian J Med Res 1976;64(5):754-757.

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Electronic Code of Federal Regulations. Title 21. Part 182 -- Substances Generally Recognized As Safe. Available at: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=182

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Fotisch K, Fäh J, Wüthrich B, et al. IgE antibodies specific for carbohydrates in a patient allergic to gum arabic (Acacia senegal). Allergy. 1998 Nov;53(11):1043-51. View abstract.

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