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Acetyl-L-Carnitine

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Are there any interactions with medications?



Acenocoumarol (Sintrom)
Interaction Rating: Major Do not take this combination.

Acenocoumarol (Sintrom) is used to slow blood clotting. Acetyl-L-carnitine might increase the effectiveness of acenocoumarol (Sintrom). Increasing the effectiveness of acenocoumarol (Sintrom) might slow blood clotting too much. This might increase the change of bruising and bleeding. The dose of your acenocoumarol (Sintrom) might need to be changed.



Warfarin (Coumadin)
Interaction Rating: Moderate Be cautious with this combination.
Talk with your health provider.

Warfarin (Coumadin) is used to slow blood clotting. Acetyl-L-carnitine might increase the effects of warfarin (Coumadin) and increase the chances of bruising and bleeding. Be sure to have your blood checked regularly. The dose of your warfarin (Coumadin) might need to be changed.

Dosing considerations for Acetyl-l-carnitine.

The following doses have been studied in scientific research:

BY MOUTH:
  • For age-related memory loss: 1500-2000 mg of acetyl-L-carnitine has been used daily for 3 months.
  • For age-related tiredness: 2 grams of acetyl-L-carnitine has been used twice daily for 180 days.
  • For age-related testosterone deficiency: 2 grams of acetyl-L-carnitine plus 2 grams of propionyl-L-carnitine has been used daily for 6 months.
  • For alcohol withdrawal: 1-3 grams of acetyl-L-carnitine has been administered by IV for 10 days. Then for the next 80 days, 3 grams of acetyl-L-carnitine has been taken by mouth daily.
  • For Alzheimer's disease: 1500-3000 mg of acetyl-L-carnitine has been taken by mouth daily in two or three divided doses for 3-12 months.
  • For improving memory in people who use alcohol excessively: 2 grams of acetyl-L-carnitine has been used daily for 90 days.
  • For nerve pain in people with diabetes: 1500-3000 mg of acetyl-L-carnitine has been taken by mouth daily in divided doses for one year. In some cases, 1000 mg of acetyl-L-carnitine was injected into the muscles for 10-15 days before it was taken by mouth.
  • For poor brain function in people with liver disease (hepatic encephalopathy): 2 grams of acetyl-L-carnitine has been taken twice daily for 90 days.
  • For male infertility:
    • 1 gram of acetyl-L-carnitine plus 2 grams of L-carnitine has been taken daily to treat male infertility
    • For male infertility secondary to abacterial prostatovesiculoepididymitis: 500 mg of acetyl-L-carnitine plus 1 gram of L-carnitine every 12 hours has been used following 2 months of treatment with nonsteroidal anti-inflammatory drugs (NSAIDs).
    • For male infertility due to low sperm movement: A combination containing 1660 mg of L-arginine, 150 mg of L-carnitine, 50 mg of acetyl-L-carnitine, and 200 mg of Panax ginseng has been taken daily for 3 months.
    • For male infertility due to prostate swelling caused by Chlamydia infection: A combination containing 1660 mg of L-arginine, 150 mg of L-carnitine, 50 mg of acetyl-L-carnitine, and 200 mg of Panax ginseng has been taken daily for 6 months along with 600 mg of prulifloxacin.
  • For Peyronie's disease: 1 gram of acetyl-L-carnitine has been taken twice daily for 3 months.
  • BY IV:
  • For alcohol withdrawal: 1-3 grams of acetyl-L-carnitine has been given by IV over 3-4 hours for 10 days. Thereafter, 3 grams of acetyl-L-carnitine has been taken by mouth daily for 80 days.
  • For improving blood flow to the brain: A single dose of 1500 mg of acetyl-L-carnitine has been given by IV.
AS A SHOT:
  • For nerve pain caused by diabetes: 1000 mg of acetyl-L-carnitine has been given as a shot daily for 10-15 days. In some cases, 2000 mg of acetyl-L-carnitine has been taken by mouth daily for 12 months following the shots.

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