Aczone (Dapzone) vs. Acanya, Benzaclin

Are Aczone and Acanya, Benzaclin the Same Thing?

Dapsone and Acanya or Benzaclin (clindamycin phosphate 1.2% and benzoyl peroxide 2.5%) are antibacterial medications used to treat different skin conditions.

Dapsone is an oral medication used in the treatment of dermatitis herpetiformis (a skin condition) and leprosy (Hansen's disease).

Acanya and Benzaclin for topical use also contain a keratolytic agent and are used to treat acne.

A brand name for dapsone is Aczone.

Side effects of dapsone that are different from Acanya or Benzaclin include nausea, vomiting, loss of appetite, dizziness, blurred vision, ringing in the ears, headache, sleep problems (insomnia), or increased sensitivity of the skin to sunlight.

Side effects of Acanya or Benzaclin that are different from dapsone include skin irritation such as burning or stinging, itching or tingly feeling, dryness or peeling of treated skin, or redness or other irritation.

Dapsone may interact with other drugs.

Acanya or Benzaclin may interact with other topical antibiotics.

What Are Possible Side Effects of Aczone?

Side effects of Aczone include:

  • skin dryness,
  • redness,
  • oiliness, and
  • peeling.

What Are Possible Side Effects of Acanya, Benzaclin?

Common side effects of Acanya, Benzaclin include:

  • skin irritation such as burning or stinging,
  • itching or tingly feeling,
  • dryness or peeling of treated skin, or
  • redness or other irritation.

Tell your doctor if you have serious side effects of Acanya including:

  • severe redness, burning, stinging, or peeling of treated skin areas; or
  • diarrhea that is watery or bloody.

What Is Aczone?

Aczone (dapsone) Gel, 5% is a sulfone drug indicated for the topical treatment of acne vulgaris. Aczone Gel 5% is available in generic form.

What Is Acanya, Benzaclin?

Acanya (clindamycin phosphate 1.2% and benzoyl peroxide 2.5%) for topical use is a combination of an antibiotic and an antibacterial and keratolytic agent used to treat acne.


Acne is the result of an allergy. See Answer

What Drugs Interact With Aczone?

Aczone Gel 5% may interact with other topical medications, harsh or abrasive soaps, or cosmetics on the affected area. Tell your doctor all medications, supplements, and skin care products you use. Tell your doctor if you are pregnant or plan to become pregnant before using Aczone Gel 5%; it is unknown if it will harm a fetus. Aczone Gel 5% passes into breast milk and may affect a nursing baby. Consult your doctor before breastfeeding.

What Drugs Interact With Acanya, Benzaclin?

Tell your doctor all medications you use. Do not get Acanya in your mouth, eyes, vagina, or on your lips. Do not use Acanya, Benzaclin if you have Crohn's disease, ulcerative colitis, or severe diarrhea with past antibiotic use. If you are pregnant, only use Acanya, Benzaclin if the potential benefit outweighs the potential risk to the fetus. Talk to your doctor about using Acanya, Benzaclin if you are breastfeeding.

How Should Aczone Be Taken?

For topical use only. Not for oral, ophthalmic, or intravaginal use. After the skin is gently washed and patted dry, apply approximately a pea-sized amount of Aczone Gel 5%, in a thin layer to the acne affected areas twice daily. Rub in Aczone Gel 5% gently and completely. Wash hands after application of Aczone Gel 5%.

How Should Acanya, Benzaclin Be Taken?

The recommended dosage of Acanya is a pea sized amount applied to your face once a day. Other topical antibiotics can interact with Acanya.


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Bausch Health Companies Inc. Aczone Product Information.

Almirall, LLC. Aczone Product Information.

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