Last updated on RxList: 3/18/2021
AfterPill Side Effects Center

Medical Editor: John P. Cunha, DO, FACOEP

What Is AfterPill?

AfterPill (levonorgestrel tablet) is emergency contraception that helps prevent pregnancy after birth control failure or unprotected sex. It is a backup method of preventing pregnancy and should not be used as regular birth control.

What Are Side Effects of AfterPill?

Common side effects of AfterPill include:

  • changes in menstrual periods (heavier or lighter, early or late),
  • nausea,
  • lower abdominal pain,
  • tiredness,
  • headache,
  • dizziness, and
  • breast tenderness

Dosage for AfterPill

Take one AfterPill as soon as possible within 72 hours (3 days) after unprotected sex. The sooner you take it the better it will work. If you vomit within 2 hours after taking the medication, call a healthcare professional to find out if you should repeat the dose.

What Drugs, Substances, or Supplements Interact with AfterPill?

AfterPill may interact with other drugs. Tell your doctor all medications and supplements you use.

AfterPill During Pregnancy and Breastfeeding

Tell your doctor if you are pregnant or plan to become pregnant before using AfterPill; AfterPill will not work if you are already pregnant and will not affect an existing pregnancy. Consult your doctor before breastfeeding.

Additional Information

Our AfterPill (levonorgestrel tablet) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


Choosing Your Birth Control Method See Slideshow
AfterPill Consumer Information

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using birth control pills and call your doctor at once if you have:

  • signs of a stroke--sudden numbness or weakness (especially on one side of the body), severe headache, slurred speech, balance problems;
  • signs of a blood clot--sudden vision loss, stabbing chest pain, feeling short of breath, coughing up blood, swelling or redness in an arm or leg;
  • heart attack symptoms--chest pain or pressure, pain spreading to your jaw or shoulder, nausea, sweating;
  • liver problems--loss of appetite, upper stomach pain, tiredness, fever, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
  • increased blood pressure--severe headache, blurred vision, pounding in your neck or ears;
  • swelling in your hands, ankles, or feet;
  • changes in the pattern or severity of migraine headaches;
  • a breast lump; or
  • symptoms of depression--sleep problems, weakness, tired feeling, mood changes.

Common side effects may include:

  • nausea, vomiting (especially when you first start taking this medicine);
  • breast tenderness;
  • breakthrough bleeding;
  • acne, darkening of facial skin;
  • weight gain; or
  • problems with contact lenses.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Read the entire detailed patient monograph for AfterPill (Levonorgestrel) Tablet, 1.5 mg)


Which of the following are methods for contraception? See Answer
AfterPill Professional Information


No information provided.

Read the entire FDA prescribing information for AfterPill (Levonorgestrel) Tablet, 1.5 mg)

© AfterPill Patient Information is supplied by Cerner Multum, Inc. and AfterPill Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.

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