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Agrylin

Last reviewed on RxList: 3/18/2021
Agrylin Patient Information Including Side Effects

Brand Names: Agrylin

Generic Name: anagrelide

What is anagrelide (Agrylin)?

Anagrelide is used to treat a blood cell disorder called thrombocythemia (also called thrombocytosis), which occurs when your body produces too many platelet cells.

Anagrelide may also be used for purposes not listed in this medication guide.

What are the possible side effects of anagrelide (Agrylin)?

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • easy bruising or bleeding (nosebleeds, bleeding gums);
  • signs of stomach bleeding--bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds;
  • chest pain or pressure;
  • fast or pounding heartbeats, fluttering in your chest, and sudden dizziness (like you might pass out);
  • shortness of breath;
  • swelling in your lower legs; or
  • blue colored lips or skin.

Common side effects may include:

  • fast heartbeats, chest pain, breathing problems;
  • numbness, tingling, burning pain;
  • headache, weakness, dizziness;
  • stomach pain, gas, indigestion, loss of appetite;
  • nausea, vomiting, diarrhea;
  • swelling in your hands or feet;
  • fever, cough, not feeling well;
  • back pain; or
  • rash, itching.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about anagrelide (Agrylin)?

Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.

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Agrylin Patient Information including How Should I Take

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What should I discuss with my healthcare provider before taking anagrelide (Agrylin)?

Tell your doctor if you have ever had:

It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

This medicine may affect fertility (your ability to have children).

You should not breastfeed while using anagrelide.

Anagrelide is not approved for use by anyone younger than 7 years old.

How should I take anagrelide (Agrylin)?

Your heart function may need to be checked using an electrocardiograph or ECG (sometimes called an EKG) before and during treatment. You may also need frequent blood tests while taking anagrelide.

Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.

If you need surgery, tell the surgeon ahead of time that you are using anagrelide.

Store at room temperature away from moisture, heat, and light.

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Agrylin Patient Information including If I Miss a Dose

What happens if I miss a dose (Agrylin)?

Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.

What happens if I overdose (Agrylin)?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking anagrelide (Agrylin)?

Do not take aspirin unless your doctor has told you to. Follow your doctor's instructions about how much aspirin to take, and how often to take it.

Ask a doctor or pharmacist before using any medicines for pain, fever, swelling, or cold/flu symptoms. They may contain aspirin or similar ingredients (such as ibuprofen, ketoprofen, or naproxen) which can increase your risk of bleeding.

What other drugs will affect anagrelide (Agrylin)?

Anagrelide can cause a serious heart problem. Your risk may be higher if you also use certain other medicines for infections, asthma, heart problems, high blood pressure, depression, mental illness, cancer, malaria, or HIV.

Tell your doctor about all your other medicines, especially:

  • an antidepressant;
  • medicine to improve blood flow;
  • a blood thinner (such as warfarin or Coumadin) or other medicine to treat or prevent blood clots;
  • NSAIDs (nonsteroidal anti-inflammatory drugs)--aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib, diclofenac, indomethacin, meloxicam, and others.

This list is not complete. Other drugs may affect anagrelide, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

Where can I get more information (Agrylin)?

Your pharmacist can provide more information about anagrelide.


Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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