Aklief vs. Accutane

Are Aklief and Accutane the Same Thing?

Aklief (trifarotene) Cream and Accutane (isotretinoin) are retinoids used to treat acne vulgaris.

Aklief Cream is a topical preparation and Accutane is taken orally.

Accutane (isotretinoin) is a retinoid used for the treatment and prevention of severe acne.

The brand name Accutane is discontinued in the U.S., but generic formulations are available.

Side effects of Aklief Cream that are different from Accutane include application site reactions (such as irritation, itching, pain, redness, dryness, stinging/burning, discoloration, rash, swelling, and lesions), sunburn, acne, and allergic dermatitis.

Side effects of Accutane that are different from Aklief Cream include dry skin, itching, rash, dry nose, nosebleeds, cracks in the corners of the mouth, dry mouth, dry lips, cracking or peeling skin, inflammation of the whites of the eyes, dry eyes, joint pain, back pain, dizziness, drowsiness, nervousness, and changes in your fingernails or toenails.

Aklief Cream may interact with other drugs.

Accutane may also interact with steroids, seizure medications, and tetracycline antibiotics.

What Are Possible Side Effects of Aklief?

Common side effects of Aklief include:

  • application site reactions such as:
    • irritation,
    • itching,
    • pain,
    • redness,
    • dryness,
    • stinging/burning,
    • discoloration,
    • rash,
    • swelling, and
    • lesions
  • sunburn,
  • acne, and
  • allergic dermatitis

What Are Possible Side Effects of Accutane?

Common side effects of Accutane include:

  • dry skin,
  • itching,
  • rash,
  • dry nose,
  • nosebleeds,
  • cracks in the corners of the mouth,
  • dry mouth,
  • dry lips,
  • cracking or peeling skin,
  • inflammation of the whites of the eyes,
  • dry eyes,
  • joint pain,
  • back pain,
  • dizziness,
  • drowsiness,
  • nervousness, or
  • changes in your fingernails or toenails.

What Is Aklief?

Aklief (trifarotene) Cream is a retinoid indicated for the topical treatment of acne vulgaris in patients 9 years of age and older.

What Is Accutane?

Accutane (isotretinoin) is a retinoid used for the treatment and prevention of severe acne. The brand name Accutane is discontinued in the U.S., but generic formulations are available.

SLIDESHOW

Skin Health: 15 Tips for Clear Skin See Slideshow

What Drugs Interact With Aklief?

Aklief may interact with other drugs. Tell your doctor all medications and supplements you use.

What Drugs Interact With Accutane?

Accutane may interact with steroids, seizure medications, or tetracycline antibiotics

How Should Aklief Be Taken?

The dose of Aklief Cream is a thin layer applied to the affected areas of the face and/or trunk once a day, in the evening, on clean and dry skin.

How Should Accutane Be Taken?

The recommended dose of Accutane is 0.5 to 2 mg per kg of body weight daily.

QUESTION

Acne is the result of an allergy. See Answer

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References
Galderma. Aklief Product Information.

https://www.aklief.com

FDA. Accutane Product Information.

https://www.accessdata.fda.gov/drugsatfda_docs/label/2008/018662s059lbl.pdf

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