Aklief vs. Retin-A

Are Aklief and Retin-A the Same Thing?

Aklief (trifarotene) Cream and Retin-A (tretinoin) Cream and Gel are retinoids indicated for the topical treatment of acne vulgaris.

Side effects of Aklief Cream and Retin-A that are similar include application site reactions (such as irritation, itching, pain, redness, dryness, stinging/burning, discoloration, rash, swelling, and lesions).

Side effects of Aklief Cream that are different from Retin-A include sunburn, acne, and allergic dermatitis.

Aklief Cream may interact with other drugs.

Retin-A may interact with other topical medications, especially those containing sulfur, resorcinol, or salicylic acid.

What Are Possible Side Effects of Aklief?

Common side effects of Aklief include:

  • application site reactions such as:
    • irritation,
    • itching,
    • pain,
    • redness,
    • dryness,
    • stinging/burning,
    • discoloration,
    • rash,
    • swelling, and
    • lesions
  • sunburn,
  • acne, and
  • allergic dermatitis

What Are Possible Side Effects of Retin-A?

Common side effects of Retin-A include:

  • red, swollen, blistered, or crusted skin;
  • burning,
  • warmth,
  • stinging,
  • tingling,
  • itching,
  • dryness,
  • peeling, or irritation where the medicine is applied; or
  • changes in skin color (darker or lighter)

What Is Aklief?

Aklief (trifarotene) Cream is a retinoid indicated for the topical treatment of acne vulgaris in patients 9 years of age and older.

What Is Retin-A?

Retin-A (tretinoin) Cream and Gel is a form of Vitamin A used for the topical treatment of acne vulgaris.

SLIDESHOW

Skin Health: 15 Tips for Clear Skin See Slideshow

What Drugs Interact With Aklief?

Aklief may interact with other drugs. Tell your doctor all medications and supplements you use.

What Drugs Interact With Retin-A?

Retin-A may interact with other topical medications, especially those containing sulfur, resorcinol, or salicylic acid. Tell your doctor all medications you use.

How Should Aklief Be Taken?

The dose of Aklief Cream is a thin layer applied to the affected areas of the face and/or trunk once a day, in the evening, on clean and dry skin.

How Should Retin-A Be Taken?

Apply Retin-A to infected areas once a day. Use enough to cover the entire affected area lightly. Exposure to sunlight including sunlamps should be minimized while using Retin-A. If you have a sun burn you should avoid using Retin-A until you have completely recovered from the sun burn.

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Acne is the result of an allergy. See Answer

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References
Galderma. Aklief Product Information.

https://www.aklief.com

Dailymed. Retin-A Product Information.

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=9556d73d-c573-4e0a-9feb-764ce2d1107b

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