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Last reviewed on RxList: 4/20/2020
Akovaz Side Effects Center

Medical Editor: John P. Cunha, DO, FACOEP

What Is Akovaz?

Akovaz (ephedrine sulfate injection) is an alpha- and beta- adrenergic agonist and a norepinephrine-releasing agent that is indicated for the treatment of clinically important low blood pressure (hypotension) occurring in the setting of anesthesia.

What Are Side Effects of Akovaz?

Common side effects of Akovaz include:

Dosage for Akovaz

A dose of Akovaz injection, 50 mg/mL, (equivalent to 38 mg ephedrine base) is injected intravenously as a bolus.

What Drugs, Substances, or Supplements Interact with Akovaz?

Akovaz may interact with clonidine, oxytocin and oxytocic drugs, propofol, monoamine oxidase inhibitors (MAOIs), atropine, alpha-adrenergic antagonists, beta-adrenergic antagonists, reserpine, quinidine, mephentermine, guanethidine, rocuronium, epidural anesthesia, theophylline, and cardiac glycosides. Tell your doctor all medications and supplements you use.

Akovaz During Pregnancy and Breastfeeding

Tell your doctor if you are pregnant before receiving Akovaz. It is unknown if it would affect a fetus. Akovaz passes into breast milk. Consult your doctor before breastfeeding.

Additional Information

Our Akovaz (ephedrine sulfate injection) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


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Akovaz Professional Information


The following adverse reactions associated with the use of ephedrine sulfate were identified in the literature. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to estimate their frequency reliably or to establish a causal relationship to drug exposure.

Gastrointestinal disorders: Nausea, vomiting

Cardiac disorders: Tachycardia, palpitations (thumping heart), reactive hypertension, bradycardia, ventricular ectopics, R-R variability

Nervous system disorders: Dizziness

Psychiatric disorders: Restlessness

Read the entire FDA prescribing information for Akovaz (Ephedrine Sulfate Injection)


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© Akovaz Patient Information is supplied by Cerner Multum, Inc. and Akovaz Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.

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