Slideshows Images Quizzes

Copyright © 2018 by RxList Inc. RxList does not provide medical advice, diagnosis or treatment. See additional information.

Aldactone vs. Accutane

Are Aldactone and Accutane the Same Thing?

Aldactone (spironolactone) and Accutane (isotretinoin) are used to treat acne.

Aldactone is used off-label for acne. Aldactone is typically used to reduce fluid retention (edema) caused by heart, liver or kidney problems, high blood pressure (hypertension), and certain patients with hyperaldosteronism.

The brand name Accutane is discontinued in the U.S., but generic versions are available.

Aldactone is an aldosterone receptor antagonist and Accutane is a retinoid.

What Are Possible Side Effects of Aldactone?

Common side effects of Aldactone include:

Tell your doctor if you have serious side effects of Aldactone including irregular heart rate, muscle pain or weakness, urinating less than usual, shallow breathing, tremors, confusion, or a severe skin reaction, hyperkalemia (high levels of potassium in the blood), and numbness.

What Are Possible Side Effects of Accutane?

Common side effects of Accutane include:

What Is Aldactone?

Aldactone (spironolactone) is an aldosterone receptor antagonist that causes the kidneys to remove water and sodium from the body, with reduced losses of potassium. Aldactone is used to reduce edema caused by heart, liver or kidney problems, high blood pressure (hypertension), and certain patients with hyperaldosteronism.

What Is Accutane?

Accutane (isotretinoin) is a retinoid used for the treatment and prevention of severe acne. The brand name Accutane is discontinued in the U.S., but generic formulations are available.

SLIDESHOW

Skin Health: 15 Tips for Clear Skin See Slideshow

What Drugs Interact With Aldactone?

Aldactone may interact with lithium or steroids.

Aldactone may also interact with other medicines that make you sleepy (such as cold or allergy medicine, sedatives, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression, or anxiety), digoxin, ACE inhibitors, or nonsteroidal anti-inflammatory drugs (NSAIDs).

What Drugs Interact With Accutane?

Accutane may interact with steroids, seizure medications, or tetracycline antibiotics

How Should Aldactone Be Taken?

Aldactone is available in 25, 50 and 100 mg tablets. Because of tumor formation in experimental animals, use in pregnancy should be avoided unless the benefits outweigh the potential risks to the fetus; women who are breastfeeding are advised not to use Aldactone. In addition, the drug should not be used to decrease the normal edema of pregnancy. An active metabolite of Aldactone appears in breast milk. Breastfeeding while using Aldactone is not recommended. If use of Aldactone is deemed essential, an alternative method of infant feeding should be used.

How Should Accutane Be Taken?

The recommended dose of Accutane is 0.5 to 2 mg per kg of body weight daily.

QUESTION

Acne is the result of an allergy. See Answer
Disclaimer

All drug information provided on RxList.com is sourced directly from drug monographs published by the U.S. Food and Drug Administration (FDA).

Any drug information published on RxList.com regarding general drug information, drug side effects, drug usage, dosage, and more are sourced from the original drug documentation found in its FDA drug monograph.

Drug information found in the drug comparisons published on RxList.com is primarily sourced from the FDA drug information. The drug comparison information found in this article does not contain any data from clinical trials with human participants or animals performed by any of the drug manufacturers comparing the drugs.

The drug comparisons information provided does not cover every potential use, warning, drug interaction, side effect, or adverse or allergic reaction. RxList.com assumes no responsibility for any healthcare administered to a person based on the information found on this site.

As drug information can and will change at any time, RxList.com makes every effort to update its drug information. Due to the time-sensitive nature of drug information, RxList.com makes no guarantees that the information provided is the most current.

Any missing drug warnings or information does not in any way guarantee the safety, effectiveness, or the lack of adverse effects of any drug. The drug information provided is intended for reference only and should not be used as a substitute for medical advice.

If you have specific questions regarding a drug’s safety, side effects, usage, warnings, etc., you should contact your doctor or pharmacist, or refer to the individual drug monograph details found on the FDA.gov or RxList.com websites for more information.

You may also report negative side effects of prescription drugs to the FDA by visiting the FDA MedWatch website or calling 1-800-FDA-1088.

References

Pfizer. Aldactone Product Information.
https://www.pfizermedicalinformation.com/en-us/aldactone
FDA. Accutane Product Information.
https://www.accessdata.fda.gov/drugsatfda_docs/label/2008/018662s059lbl.pdf
CONTINUE SCROLLING FOR RELATED SLIDESHOW

Health Solutions From Our Sponsors