Aldactone vs. Proscar

Are Aldactone and Proscar the Same Thing?

Aldactone (spironolactone) and Proscar (finasteride) are used off-label to treat women with male-pattern hair loss. Currently both drugs are only FDA-approved for use in men.

Aldactone is also used to reduce fluid retention (edema) caused by heart, liver or kidney problems, high blood pressure (hypertension), and certain patients with hyperaldosteronism.

What Are Possible Side Effects of Aldactone?

Common side effects of Aldactone include:

  • skin rash,
  • headache,
  • dizziness,
  • nausea,
  • vomiting,
  • gas, and
  • stomach pain.

Tell your doctor if you have serious side effects of Aldactone including irregular heart rate, muscle pain or weakness, urinating less than usual, shallow breathing, tremors, confusion, or a severe skin reaction, hyperkalemia (high levels of potassium in the blood), and numbness.

What Are Possible Side Effects of Proscar?

Common side effects of Proscar include:

  • impotence,
  • loss of interest in sex,
  • trouble having an orgasm,
  • abnormal ejaculation,
  • swelling in your hands or feet,
  • swelling or tenderness in your breasts,
  • dizziness,
  • weakness,
  • feeling faint,
  • headache,
  • runny nose, or
  • skin rash.

In some men, Proscar can decrease the amount of semen released during sex. This is harmless. Proscar may also increase hair growth. The sexual side effects of Proscar may continue after you stop taking it. Talk to your doctor if you have concerns about these side effects.

QUESTION

Testosterone is a chemical found only in men. See Answer

What Is Aldactone?

Aldactone (spironolactone) is an aldosterone receptor antagonist that causes the kidneys to remove water and sodium from the body, with reduced losses of potassium. Aldactone is used to reduce edema caused by heart, liver or kidney problems, high blood pressure (hypertension), and certain patients with hyperaldosteronism.

What Is Proscar?

Proscar (finasteride) is an inhibitor of steroid Type II 5a-reductase, that works by decreasing the amount of a natural body hormone dihydrotestosterone (DHT) that causes growth of the prostate, and is used to treat symptoms of benign prostatic hyperplasia (BPH) in men with an enlarged prostate. Proscar is available in generic form.

What Drugs Interact With Aldactone?

Aldactone may interact with lithium or steroids.

Aldactone may also interact with other medicines that make you sleepy (such as cold or allergy medicine, sedatives, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression, or anxiety), digoxin, ACE inhibitors, or nonsteroidal anti-inflammatory drugs (NSAIDs).

What Drugs Interact With Proscar?

Proscar may interact with other drugs.

How Should Aldactone Be Taken?

Aldactone is available in 25, 50 and 100 mg tablets. Because of tumor formation in experimental animals, use in pregnancy should be avoided unless the benefits outweigh the potential risks to the fetus; women who are breastfeeding are advised not to use Aldactone. In addition, the drug should not be used to decrease the normal edema of pregnancy. An active metabolite of Aldactone appears in breast milk. Breastfeeding while using Aldactone is not recommended. If use of Aldactone is deemed essential, an alternative method of infant feeding should be used.

How Should Proscar Be Taken?

The recommended dose of Proscar is one tablet (5 mg) taken once a day.

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References
Pfizer. Aldactone Product Information.

https://www.pfizermedicalinformation.com/en-us/aldactone

Merck. Proscar Product Information.

https://www.merck.com/product/usa/pi_circulars/p/proscar/proscar_pi.pdf

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