Alder Dogwood, Arraclán, Arrow Wood, Aulne Noir, Black Dogwood, Bois Noir, Bois à Poudre, Bourdaine, Bourgène, Buckthorn, Buckthorn Bark, Coudrier Noir, Dog Wood, Frángula, Frangula, Frangula Alnus, Frangula Bark, Frangulae Cortex, Frangule, Glossy Buckthorn, Nerprun Bourdaine, Nerprun Noir, Rhamnus Frangula, Rhubarbe des Paysans.
Alder buckthorn is a plant. The aged or heated bark of the plant is used to make medicine. Don't confuse alder buckthorn with European buckthorn.
Alder buckthorn is used as a laxative, as a tonic, and as an ingredient in the Hoxsey cancer formula.
How does it work?
Alder buckthorn bark contains chemicals that work as a laxative by stimulating the intestines.
Possibly Effective for...
- Constipation. Alder buckthorn is known to contain certain chemicals that work as laxatives. Alder buckthorn seems to work about as well as cascara for relieving constipation.
Insufficient Evidence to Rate Effectiveness for...
- Other conditions.
Natural Medicines Comprehensive Database rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, and Insufficient Evidence to Rate (detailed description of each of the ratings).
Alder buckthorn is POSSIBLY SAFE for most adults when taken by mouth for less than 8-10 days. Taking alder buckthorn by mouth for more than 8-10 days is POSSIBLY UNSAFE. It might cause low potassium; heart problems; stomach problems; muscle weakness; and blood problems, including blood in the urine. Some people get uncomfortable cramps from alder buckthorn. If you experience diarrhea or watery stools while using alder buckthorn, stop taking it.
The fresh bark can cause severe vomiting. Make sure you are using a bark product that is at least one year old or has been heat processed.
Children: Alder buckthorn is LIKELY UNSAFE when taken by mouth by children younger than 12 years of age.
Diarrhea: Don't use alder buckthorn if you have diarrhea. Its laxative effects may worsen this condition.
Intestinal disorders, including intestinal blockage, appendicitis, Crohn's disease, irritable bowel syndrome (IBS), or ulcerative colitis: Don't take alder buckthorn if you have a bowel obstruction; appendicitis; unexplained stomach pain; or inflammatory conditions of the intestines including Crohn's disease, colitis, and irritable bowel syndrome (IBS).
Digoxin (Lanoxin)Interaction Rating: Moderate Be cautious with this combination.Talk with your health provider.
Alder buckthorn is a type of laxative called a stimulant laxative. Stimulant laxatives can decrease potassium levels in the body. Low potassium levels can increase the risk of side effects of digoxin (Lanoxin).
Medications for inflammation (Corticosteroids)Interaction Rating: Moderate Be cautious with this combination.Talk with your health provider.
Some medications for inflammation can decrease potassium in the body. Alder buckthorn is a type of laxative that might also decrease potassium in the body. Taking alder buckthorn along with some medications for inflammation might decrease potassium in the body too much.
Medications taken by mouth (Oral drugs)Interaction Rating: Moderate Be cautious with this combination.Talk with your health provider.
Alder buckthorn is a laxative. Laxatives can decrease how much medicine your body absorbs. Decreasing how much medicine your body absorbs can decrease the effectiveness of your medication.
Stimulant laxativesInteraction Rating: Moderate Be cautious with this combination.Talk with your health provider.
Alder buckthorn is a type of laxative called a stimulant laxative. Stimulant laxatives speed up the bowels. Taking alder buckthorn along with other stimulant laxatives could speed up the bowels too much and cause dehydration and low minerals in the body.
Some stimulant laxatives include bisacodyl (Correctol, Dulcolax), cascara, castor oil (Purge), senna (Senokot) and others.
Warfarin (Coumadin)Interaction Rating: Moderate Be cautious with this combination.Talk with your health provider.
Alder buckthorn can work as a laxative. In some people alder buckthorn can cause diarrhea. Diarrhea can increase the effects of warfarin and increase the risk of bleeding. If you take warfarin do not to take excessive amounts of alder buckthorn.
Water pills (Diuretic drugs)Interaction Rating: Moderate Be cautious with this combination.Talk with your health provider.
Alder buckthorn is a laxative. Some laxatives can decrease potassium in the body. "Water pills" can also decrease potassium in the body. Taking alder buckthorn along with "water pills" might decrease potassium in the body too much.
The following doses have been studied in scientific research:
- For constipation: the typical dose of alder buckthorn is 0.5-2.5 grams of the dried bark. Take only the amount of bark needed to produce a soft stool. Alder buckthorn is also taken as a tea. The tea is prepared by steeping 2 grams of the herb in 150 mL of boiling water for 5-10 minutes and then straining. Alder buckthorn is also available as a liquid extract. The common dose of the liquid extract: (1:1 in 25% alcohol) is 2-5 mL three times daily. This preparation should be used only if diet change and bulk-forming laxatives don't work. Don't use the extract for more than seven to ten days.
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Ammar, R. B., Bouhlel, I., Valenti, K., Sghaier, M. B., Kilani, S., Mariotte, A. M., Dijoux-Franca, M. G., Laporte, F., Ghedira, K., and Chekir-Ghedira, L. Transcriptional response of genes involved in cell defense system in human cells stressed by H2O2 and pre-treated with (Tunisian) Rhamnus alaternus extracts: combination with polyphenolic compounds and classic in vitro assays. Chem Biol Interact. 7-20-2007;168(3):171-183. View abstract.
Ammar, R. B., Kilani, S., Bouhlel, I., Ezzi, L., Skandrani, I., Boubaker, J., Sghaier, M. B., Naffeti, A., Mahmoud, A., Chekir-Ghedira, L., and Ghedira, K. Antiproliferative, antioxidant, and antimutagenic activities of flavonoid-enriched extracts from (Tunisian) Rhamnus alaternus L.: combination with the phytochemical composition. Drug Chem Toxicol 2008;31(1):61-80. View abstract.
Ammar, R. B., Sghaier, M. B., Boubaker, J., Bhouri, W., Naffeti, A., Skandrani, I., Bouhlel, I., Kilani, S., Ghedira, K., and Chekir-Ghedira, L. Antioxidant activity and inhibition of aflatoxin B1-, nifuroxazide-, and sodium azide-induced mutagenicity by extracts from Rhamnus alaternus L. Chem Biol Interact. 7-10-2008;174(1):1-10. View abstract.
Ascherio, A., Bermudez, C. S., and Garcia, D. Outbreak of buckthorn paralysis in Nicaragua. J Trop Pediatr 1992;38(2):87-89. View abstract.
Banach, K. [Acute anthra compound poisoning caused by ingestion of buckthorn fruits]. Wiad.Lek. 3-1-1980;33(5):405-408. View abstract.
Calderon-Gonzalez, R. and Rizzi-Hernandez, H. Buckthorn polyneuropathy. N.Engl J Med 7-13-1967;277(2):69-71. View abstract.
Carrada-Bravo, T., Lopez-Leal, H., Vazquez-Arias, G., and Ley-Lopez, A. [Epidemic outbreak of polyradiculoneuritis caused by buckthorn Karwinskia humboldtiana]. Bol.Med Hosp.Infant Mex. 1983;40(3):139-147. View abstract.
Giavina-Bianchi, P. F., Jr., Castro, F. F., Machado, M. L., and Duarte, A. J. Occupational respiratory allergic disease induced by Passiflora alata and Rhamnus purshiana. Ann.Allergy Asthma Immunol 1997;79(5):449-454. View abstract.
Huang, H. C., Lee, C. R., Chao, P. D., Chen, C. C., and Chu, S. H. Vasorelaxant effect of emodin, an anthraquinone from a Chinese herb. Eur J Pharmacol 12-3-1991;205(3):289-294. View abstract.
Mai, L. P., Gueritte, F., Dumontet, V., Tri, M. V., Hill, B., Thoison, O., Guenard, D., and Sevenet, T. Cytotoxicity of Rhamnosylanthraquinones and Rhamnosylanthrones from Rhamnus nepalensis. J Nat Prod. 2001;64(9):1162-1168. View abstract.
Manojlovic, N. T., Solujic, S., Sukdolak, S., and Milosev, M. Antifungal activity of Rubia tinctorum, Rhamnus frangula and Caloplaca cerina. Fitoterapia 2005;76(2):244-246. View abstract.
Matev, M., Chakurski, I., Stefanov, G., Koichev, A., and Angelov, I. [Use of an herbal combination with laxative action on duodenal peptic ulcer and gastroduodenitis patients with a concomitant obstipation syndrome]. Vutr.Boles. 1981;20(6):48-51. View abstract.
Mitchell, J., Weller, R. O., Evans, H., Arai, I., and Daves, G. D., Jr. Buckthorn neuropathy: effects of intraneural injection of Karwinskia humboldtiana toxins. Neuropathol.Appl.Neurobiol. 1978;4(2):85-97. View abstract.
Ocampo-Roosens, L. V., Ontiveros-Nevares, P. G., and Fernandez-Lucio, O. Intoxication with buckthorn (Karwinskia humboldtiana): report of three siblings. Pediatr Dev Pathol. 2007;10(1):66-68. View abstract.
Siegers, C. P., Hertzberg-Lottin, E., Otte, M., and Schneider, B. Anthranoid laxative abuse--a risk for colorectal cancer? Gut 1993;34(8):1099-1101. View abstract.
Turner, N. J. and Hebda, R. J. Contemporary use of bark for medicine by two Salishan native elders of southeast Vancouver Island, Canada. J Ethnopharmacol 1990;29(1):59-72. View abstract.
van Gorkom, B. A., de Vries, E. G., Karrenbeld, A., and Kleibeuker, J. H. Review article: anthranoid laxatives and their potential carcinogenic effects. Aliment.Pharmacol Ther 1999;13(4):443-452. View abstract.
Verschaeve, L., Kestens, V., Taylor, J. L., Elgorashi, E. E., Maes, A., Van Puyvelde, L., De Kimpe, N., and Van Staden, J. Investigation of the antimutagenic effects of selected South African medicinal plant extracts. Toxicol In Vitro 2004;18(1):29-35. View abstract.
Willems, M., van Buuren, H. R., and de, Krijger R. Anthranoid self-medication causing rapid development of melanosis coli. Neth.J Med 2003;61(1):22-24. View abstract.
Chakurski I, Matev M, Koichev A, et al. [Treatment of chronic colitis with an herbal combination of Taraxacum officinale, Hipericum perforatum, Melissa officinaliss, Calendula officinalis and Foeniculum vulgare]. Vutr Boles. 1981;20:51-4. View abstract.
Nusko G, Schneider B, Schneider I, et al. Anthranoid laxative use is not a risk factor for colorectal neoplasia: results of a prospective case control study. Gut 2000;46:651-5. View abstract.
Young DS. Effects of Drugs on Clinical Laboratory Tests 4th ed. Washington: AACC Press, 1995.