Slideshows Images Quizzes


Last reviewed on RxList: 5/1/2009
Alupent Side Effects Center

Medical Editor: John P. Cunha, DO, FACOEP

Last reviewed on RxList 02/07/2017

Alupent (metaproterenol sulfate) Aerosol is a bronchodilator used to treat conditions such as asthma, bronchitis, and emphysema. The brand name Alupent is discontinued, but generic versions may be available. Common side effects of Alupent (metaproterenol sulfate) include:

Tell your doctor if you experience serious side effects of Alupent including:

  • an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives), or
  • chest pains or an irregular heart beat.

The usual single dose of Alupent is two to three inhalations. Alupent may interact with beta-blockers, antidepressants, monoamine oxidase inhibitors (MAOIs), other inhaled or oral bronchodilators, caffeine, diet pills, or decongestants. Tell your doctor all medications and supplements you use. It is unknown if Alupent will be harmful to a fetus. Tell your doctor if you are pregnant or plan to become pregnant during treatment. It is unknown if this drug passes into breast milk. Consult your doctor before breastfeeding.

Our Alupent (metaproterenol sulfate) Aerosol Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Alupent Consumer Information

If you experience any of the following serious side effects, stop taking metaproterenol and seek emergency medical attention or contact your doctor immediately:

  • an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives); or
  • chest pains or an irregular heart beat.

Other, less serious side effects may be more likely to occur. Continue to take metaproterenol and talk to your doctor if you experience

  • headache, dizziness, lightheadedness, or insomnia;
  • tremor or nervousness;
  • sweating;
  • nausea, vomiting, or diarrhea; or
  • dry mouth.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. You may report side effects to FDA at 1-800-FDA-1088.

Read the entire detailed patient monograph for Alupent (Metaproterenol Sulfate)

Alupent Professional Information


Adverse reactions are similar to those noted with other sympathomimetic agents. The most frequent adverse reaction to Alupent( (metaproterenol sulfate USP) administered by metered-dose inhaler among 251 patients in 90-day controlled clinical trials was nervousness. This was reported in 6.8% of patients. Less frequent adverse experiences, occurring in 1-4% of patients were headache, dizziness, palpitations, gastrointestinal distress, tremor, throat irritation, nausea, vomiting, cough and asthma exacerbation. Tachycardia occurred in less than 1% of patients.

Read the entire FDA prescribing information for Alupent (Metaproterenol Sulfate)

Related Resources for Alupent

© Alupent Patient Information is supplied by Cerner Multum, Inc. and Alupent Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.

Health Solutions From Our Sponsors