Amaryl vs. Glucotrol

Are Amaryl and Glucotrol the Same Thing?

Amaryl (glimepiride) and Glucotrol (glipizide) are oral diabetes medicines of the sulfonylurea class used together with diet and exercise to treat type 2 (non-insulin dependent) diabetes.

Insulin or other diabetes medicines are sometimes used in combination with Amaryl if needed.

What Are Possible Side Effects of Amaryl?

Common side effects of Amaryl include:

Amaryl can cause low blood sugar (hypoglycemia). Symptoms of low blood sugar include sudden sweating, shaking, fast heartbeat, hunger, blurred vision, dizziness, or tingling hands/feet.

What Are Possible Side Effects of Glucotrol?

Common side effects of Glucotrol include:

  • diarrhea
  • constipation
  • nausea
  • vomiting
  • upset stomach
  • loss of appetite
  • headache
  • weight gain,
  • skin changes (skin rash, hives, redness, itching, and blisters)
  • gas
  • drowsiness, and
  • dizziness

Tell your doctor if you experience serious side effects of Glucotrol including easy bruising or bleeding (nosebleeds, bleeding gums), tiredness, shortness of breath, upper stomach pain, itching, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes); pale skin, fever, confusion; or throbbing headache, severe nausea and vomiting, fast or pounding heartbeats, sweating or thirst, or feeling like you might pass out.

What Is Amaryl?

Amaryl (glimepiride) is an oral diabetes medicine used together with diet and exercise to treat type 2 (non-insulin dependent) diabetes. Insulin or other diabetes medicines are sometimes used in combination with Amaryl if needed

What Is Glucotrol?

Glucotrol (glipizide) is blood glucose lowering drug of the sulfonylurea class used to help maintain glucose control in type 2 diabetics, in conjunction with an appropriate diet and exercise program. Glucotrol is available as a generic named glipizide.

QUESTION

______________ is another term for type 2 diabetes. See Answer

What Drugs Interact With Amaryl?

Amaryl with drugs that raise blood sugar, such as: isoniazid, diuretics (water pills), steroids, phenothiazines, thyroid medicine, birth control pills and other hormones, seizure medicines, and diet pills, or medicines to treat asthma, colds or allergies. Hypoglycemia (low blood sugar) may result if you take Amaryl with drugs that lower blood sugar, such as: clarithromycin, disopyramide, fluoxetine, antibiotics, non-steroidal anti-inflammatory drugs (NSAIDs), aspirin or other salicylates, blood thinners, monoamine oxidase inhibitors (MAOIs), or sulfa drugs. It may also interact with albuterol, clonidine, reserpine, or beta-blockers. Tell your doctor all medications you use.

What Drugs Interact With Glucotrol?

Many drugs may interact with Glucotrol; patients should carefully check glucose levels and inform their doctors about what medications they are taking. There are no adequate and well controlled studies of Glucotrol in pregnant women. Glucotrol (glipizide) should be used during pregnancy or breastfeeding women only if the potential benefit justifies the potential risk to the fetus and infant.

How Should Amaryl Be Taken?

The recommended starting dose of Amaryl is 1 mg or 2 mg once daily. The maximum recommended dose is 8 mg once daily.

How Should Glucotrol Be Taken?

Glucotrol is available in 5 and 10 mg strength tablets. The usual starting dose is 5 mg about 30 min before breakfast.

SLIDESHOW

Type 2 Diabetes: Signs, Symptoms, Treatments See Slideshow
Disclaimer

All drug information provided on RxList.com is sourced directly from drug monographs published by the U.S. Food and Drug Administration (FDA).

Any drug information published on RxList.com regarding general drug information, drug side effects, drug usage, dosage, and more are sourced from the original drug documentation found in its FDA drug monograph.

Drug information found in the drug comparisons published on RxList.com is primarily sourced from the FDA drug information. The drug comparison information found in this article does not contain any data from clinical trials with human participants or animals performed by any of the drug manufacturers comparing the drugs.

The drug comparisons information provided does not cover every potential use, warning, drug interaction, side effect, or adverse or allergic reaction. RxList.com assumes no responsibility for any healthcare administered to a person based on the information found on this site.

As drug information can and will change at any time, RxList.com makes every effort to update its drug information. Due to the time-sensitive nature of drug information, RxList.com makes no guarantees that the information provided is the most current.

Any missing drug warnings or information does not in any way guarantee the safety, effectiveness, or the lack of adverse effects of any drug. The drug information provided is intended for reference only and should not be used as a substitute for medical advice.

If you have specific questions regarding a drug’s safety, side effects, usage, warnings, etc., you should contact your doctor or pharmacist, or refer to the individual drug monograph details found on the FDA.gov or RxList.com websites for more information.

You may also report negative side effects of prescription drugs to the FDA by visiting the FDA MedWatch website or calling 1-800-FDA-1088.

References

Sanofi Aventis. Amaryl Product Information.
http://products.sanofi.us/amaryl/amaryl.pdf
Pfizer. Glucotrol Product Information.
http://labeling.pfizer.com/showlabeling.aspx?id=579

Health Solutions From Our Sponsors