Amaryl vs. Glucotrol

Are Amaryl and Glucotrol the Same Thing?

Amaryl (glimepiride) and Glucotrol (glipizide) are oral diabetes medicines of the sulfonylurea class used together with diet and exercise to treat type 2 (non-insulin dependent) diabetes.

Insulin or other diabetes medicines are sometimes used in combination with Amaryl if needed.

What Are Possible Side Effects of Amaryl?

Common side effects of Amaryl include:

Amaryl can cause low blood sugar (hypoglycemia). Symptoms of low blood sugar include sudden sweating, shaking, fast heartbeat, hunger, blurred vision, dizziness, or tingling hands/feet.

What Are Possible Side Effects of Glucotrol?

Common side effects of Glucotrol include:

  • diarrhea
  • constipation
  • nausea
  • vomiting
  • upset stomach
  • loss of appetite
  • headache
  • weight gain,
  • skin changes (skin rash, hives, redness, itching, and blisters)
  • gas
  • drowsiness, and
  • dizziness

Tell your doctor if you experience serious side effects of Glucotrol including easy bruising or bleeding (nosebleeds, bleeding gums), tiredness, shortness of breath, upper stomach pain, itching, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes); pale skin, fever, confusion; or throbbing headache, severe nausea and vomiting, fast or pounding heartbeats, sweating or thirst, or feeling like you might pass out.

What Is Amaryl?

Amaryl (glimepiride) is an oral diabetes medicine used together with diet and exercise to treat type 2 (non-insulin dependent) diabetes. Insulin or other diabetes medicines are sometimes used in combination with Amaryl if needed

What Is Glucotrol?

Glucotrol (glipizide) is blood glucose lowering drug of the sulfonylurea class used to help maintain glucose control in type 2 diabetics, in conjunction with an appropriate diet and exercise program. Glucotrol is available as a generic named glipizide.


Type 2 Diabetes: Signs, Symptoms, Treatments See Slideshow

What Drugs Interact With Amaryl?

Amaryl with drugs that raise blood sugar, such as: isoniazid, diuretics (water pills), steroids, phenothiazines, thyroid medicine, birth control pills and other hormones, seizure medicines, and diet pills, or medicines to treat asthma, colds or allergies. Hypoglycemia (low blood sugar) may result if you take Amaryl with drugs that lower blood sugar, such as: clarithromycin, disopyramide, fluoxetine, antibiotics, non-steroidal anti-inflammatory drugs (NSAIDs), aspirin or other salicylates, blood thinners, monoamine oxidase inhibitors (MAOIs), or sulfa drugs. It may also interact with albuterol, clonidine, reserpine, or beta-blockers. Tell your doctor all medications you use.

What Drugs Interact With Glucotrol?

Many drugs may interact with Glucotrol; patients should carefully check glucose levels and inform their doctors about what medications they are taking. There are no adequate and well controlled studies of Glucotrol in pregnant women. Glucotrol (glipizide) should be used during pregnancy or breastfeeding women only if the potential benefit justifies the potential risk to the fetus and infant.

How Should Amaryl Be Taken?

The recommended starting dose of Amaryl is 1 mg or 2 mg once daily. The maximum recommended dose is 8 mg once daily.

How Should Glucotrol Be Taken?

Glucotrol is available in 5 and 10 mg strength tablets. The usual starting dose is 5 mg about 30 min before breakfast.


______________ is another term for type 2 diabetes. See Answer

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Sanofi Aventis. Amaryl Product Information.
Pfizer. Glucotrol Product Information.

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