Amerge vs. Cafergot

Reviewed on 5/6/2020

Are Amerge and Cafergot the Same Thing?

Amerge (naratriptan) and Cafergot (ergotamine tartrate and caffeine) are headache medicines used to treat migraine headaches. Amerge and Cafergot will only treat a headache that has already begun. Amerge and Cafergot will not prevent headaches or reduce the number of attacks.

Amerge and Cafergot are different types of migraine medications. Amerge is a 5HT agonist (a “triptan”) and Cafergot is a combination of an ergot alkaloid and a stimulant.

Side effects of Amerge and Cafergot that are similar include weakness and dizziness.

Side effects of Amerge that are different from Cafergot include flushing (warmth, redness, or tingling under your skin), sensations of tingling/numbness/prickling/heat/warmth under your skin, drowsiness, tired feeling, and pressure or heavy feeling in any part of your body.

Side effects of Cafergot that are different from Amerge include nausea, vomiting, upset stomach, restlessness, trouble sleeping, dizziness, spinning sensation, and itching.

Both Amerge and Cafergot may interact with other migraine headache medicines and antidepressants.

Amerge may also interact with medicines to treat psychiatric disorders, narcotics (opioids), and medicines to prevent nausea and vomiting.

Cafergot may also interact with macrolide antibiotics, protease inhibitors, antifungals, grapefruit and grapefruit juice, aprepitant, cimetidine, cyclosporine, haloperidol, imatinib, nicotine, diet pills, stimulants, ADHD medications, heart or blood pressure medications, HIV/AIDS medications, and medicines to treat asthma, colds or allergies.

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What Are Possible Side Effects of Amerge?

Common side effects of Amerge include:

  • flushing,
  • sensations of tingling/numbness/prickling/heat/warmth under your skin,
  • weakness,
  • drowsiness,
  • tired feeling,
  • dizziness, or
  • pressure or heavy feeling in any part of your body

What Are Possible Side Effects of Cafergot?

Common side effects of Cafergot include:

  • nausea,
  • vomiting,
  • upset stomach,
  • restlessness,
  • trouble sleeping,
  • dizziness,
  • spinning sensation,
  • weakness, or
  • itching

What is Amerge?

Amerge (naratriptan) is a headache medicine used to treat migraine headaches. Amerge will only treat a headache that has already begun. Amerge will not prevent headaches or reduce the number of attacks. Amerge is available in generic form.

What is Cafergot?

Cafergot (ergotamine tartrate and caffeine) is a combination of an ergot alkaloid and a stimulant used to treat a migraine type headache. Cafergot will only treat a headache that has already begun. Cafergot will not prevent migraine headaches or reduce the number of attacks. Cafergot should not be used to treat common tension headaches or any headache that seems to be different from your usual migraine headaches.

What Drugs Interact With Amerge?

Amerge may interact with other migraine headache medicines, or antidepressants. Tell your doctor all medications you use. Amerge should be used only when prescribed during pregnancy. It is unknown if this drug passes into breast milk. Consult your doctor before breastfeeding.

What Drugs Interact With Cafergot?

Cafergot (ergotamine tartrate and caffeine) is a combination of an ergot alkaloid and a stimulant used to treat a migraine type headache. Cafergot will only treat a headache that has already begun. Cafergot will not prevent migraine headaches or reduce the number of attacks. Cafergot should not be used to treat common tension headaches or any headache that seems to be different from your usual migraine headaches.

How Should Amerge be Taken?

The dosage of Amerge is 25 mg four times a day.

QUESTION

Who suffers more frequently from migraine headaches? See Answer

How Should Cafergot be Taken?

Dosage of Cafergot should start at the first sign of an attack. Adult dose is 2 tablets at the start of an attack; 1 additional tablet every 1/2 hour, if needed for full relief (maximum 6 tablets per attack, 10 per week).

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References
GSK. Amerge Prescribing Information.

https://www.gsksource.com/pharma/content/dam/GlaxoSmithKline/US/en/Prescribing_Information/Amerge/pdf/AMERGE-PI-PIL.PDF

Dailymed. Cafergot Product Information.

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=b4a06de6-f837-43a8-ae7a-aadb38dd2a7d

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