Amerge vs. Zomig

Reviewed on 5/12/2020

Are Amerge and Zomig the Same Thing?

Amerge (naratriptan) and Zomig (zolmitriptan) Nasal Spray are headache medicines (“triptans”) used to treat migraine headaches. Amerge and Zomig will only treat a headache that has already begun. Amerge and Zomig will not prevent headaches or reduce the number of attacks.

Side effects of Amerge and Zomig that are similar include flushing (warmth, redness, or tingling under your skin), weakness, drowsiness, dizziness, and pressure or heavy feeling in any part of your body.

Side effects of Amerge that are different from Zomig include sensations of tingling/numbness/prickling/heat/warmth under your skin and tired feeling.

Side effects of Zomig that are different from Amerge include unusual or unpleasant taste in your mouth, discomfort in the nose or throat after using the nasal spray, nausea, and dry mouth.

Both Amerge and Zomig may interact with other migraine headache medicines, antidepressants, medicine to treat a psychiatric disorder, narcotics (opioids), and medicines to prevent nausea and vomiting.

Zomig may also interact with cimetidine.

What Are Possible Side Effects of Amerge?

Common side effects of Amerge include:

  • flushing,
  • sensations of tingling/numbness/prickling/heat/warmth under your skin,
  • weakness,
  • drowsiness,
  • tired feeling,
  • dizziness, or
  • pressure or heavy feeling in any part of your body

What Are Possible Side Effects of Zomig?

Common side effects of Zomig include:

  • unusual or unpleasant taste in your mouth,
  • discomfort in the nose or throat after using the nasal spray,
  • warmth/redness/tingling/numbness under the skin,
  • nausea,
  • dry mouth,
  • weakness,
  • drowsiness,
  • dizziness, or
  • pressure or heavy feeling in any part of your body

What is Amerge?

Amerge (naratriptan) is a headache medicine used to treat migraine headaches. Amerge will only treat a headache that has already begun. Amerge will not prevent headaches or reduce the number of attacks. Amerge is available in generic form.

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What Is Zomig?

Zomig (zolmitriptan) Nasal Spray is a headache medicine that narrows blood vessels around the brain used to treat migraine headaches. Zomig Nasal Spray will only treat a headache that has already begun. Zomig Nasal Spray will not prevent headaches or reduce the number of attacks.

What Drugs Interact With Amerge?

 Amerge may interact with other migraine headache medicines, or antidepressants. Tell your doctor all medications you use. Amerge should be used only when prescribed during pregnancy. It is unknown if this drug passes into breast milk. Consult your doctor before breastfeeding.

What Drugs Interact With Zomig?

Zomig may interact with other migraine headache medicines, cimetidine, or antidepressants. Tell your doctor all medications you are taking. During pregnancy, Zomig should be used only when prescribed. It is unknown if this drug passes into breast milk. Consult your doctor before breast-feeding.

Zomig may also interact with alcohol, oral contraceptives, and carbonic anhydrase inhibitors.

How Should Amerge be Taken?

The dosage of Amerge is 25 mg four times a day.

How Should Zomig Be Taken?

The initial dose of Zomig is 2.5 mg or less. The dose can be repeated after 2 hours if symptoms persist. The maximum dose is 10 mg per day.

Disclaimer

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References
GSK. Amerge Prescribing Information.

https://www.gsksource.com/pharma/content/dam/GlaxoSmithKline/US/en/Prescribing_Information/Amerge/pdf/AMERGE-PI-PIL.PDF

Amneal Pharmaceuticals LLC. Zomig Product Information

https://zomig.com/

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