Slideshows Images Quizzes


Last reviewed on RxList: 1/10/2017
Amikin Side Effects Center

Last reviewed on RxList 10/6/2016

Amikin (amikacin) is an aminoglycoside antibiotic used to treat serious bacterial infections. The brand name Amikin is no longer available in the U.S. Generic versions may still be available. Side effects of Amikin (amikacin) include:

  • nausea,
  • vomiting,
  • loss of appetite,
  • increased thirst,
  • rash, or
  • injection site reactions (pain, irritation, redness).

Amikin is administered as an intravenous or intramuscular injection and the dose is determined by the patient's body weight. Amikin may interact with other drugs, especially those that affect the kidneys. Tell your doctor all medications and supplements you use. Aminoglycosides, including Amikin, can cause fetal harm when administered to a pregnant woman. If this drug is used during pregnancy, or if the patient becomes pregnant while taking this drug, the patient should be apprised of the potential hazard to the fetus. It is not known whether this drug is excreted in human milk. Consult your doctor before breastfeeding.

Our Amikin Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Amikin Consumer Information

If you experience any of the following serious side effects, stop taking amikacin and seek emergency medical attention:

  • an allergic reaction (shortness of breath; closing of the throat; hives; swelling of the lips, face, or tongue; rash; or fainting);
  • little or no urine;
  • decreased hearing or ringing in the ears;
  • dizziness, clumsiness, or unsteadiness;
  • numbness, skin tingling, muscle twitching, or seizures; or
  • severe watery diarrhea and abdominal cramps.

Other, less serious side effects may be more likely to occur. Continue to take amikacin and talk to your doctor if you experience

  • increased thirst;
  • loss of appetite;
  • nausea or vomiting;
  • a rash.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. You may report side effects to FDA at 1-800-FDA-1088.

Read the entire detailed patient monograph for Amikin (Amikacin)

Amikin Professional Information


All aminoglycosides have the potential to induce auditory, vestibular, and renal toxicity and neuromuscular blockade (see DESCRIPTION: WARNINGS box). They occur more frequently in patients with present or past history of renal impairment, of treatment with other ototoxic or nephrotoxic drugs, and in patients treated for longer periods and/or with higher doses than recommended.

Neurotoxicity-Ototoxicity: Toxic effects on the eighth cranial nerve can result in hearing loss, loss of balance, or both. Amikacin primarily affects auditory function. Cochlear damage includes high frequency deafness and usually occurs before clinical hearing loss can be detected.

Neurotoxicity-Neuromuscular Blockage: Acute muscular paralysis and apnea can occur following treatment with aminoglycoside drugs.

Nephrotoxicity: Elevation of serum creatinine, albuminuria, presence of red and white cells, casts, azotemia, and oliguria have been reported. Renal function changes are usually reversible when the drug is discontinued.

Other: In addition to those described above, other adverse reactions which have been reported o nrare occasions are skin rash, drug fever, headache, paresthesia, tremor, nausea and vomiting, eosinophilia, arthralgia, anemia, and hypotension.

Read the entire FDA prescribing information for Amikin (Amikacin)

Related Resources for Amikin

© Amikin Patient Information is supplied by Cerner Multum, Inc. and Amikin Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.

Health Solutions From Our Sponsors