Medical Editor: John P. Cunha, DO, FACOEP
Aminosyn-HF 8% (amino acid injection) is a combination of amino acids used to treatment of hepatic encephalopathy in patients with cirrhosis or hepatitis. Aminosyn-HF 8% provides nutritional support for patients with these diseases of the liver who require parenteral nutrition and are intolerant of other general purpose amino acid injections, which are contraindicated in patients with hepatic coma. Common side effects of Aminosyn-HF 8% include:
- injection site reactions (skin redness, inflammation, warm sensation, and swelling)
- water weight gain
- increase in BUN, and
- low blood sodium
The total dose of Aminosyn-HF 8% depends upon daily protein requirements and the patient's metabolic and clinical response. Aminosyn-HF 8% may interact with other drugs. Tell your doctor all medications and supplements you use. During pregnancy, Aminosyn-HF 8% should be used only if prescribed. Consult your doctor before breastfeeding.
Our Aminosyn-HF 8% (amino acid injection) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Reactions reported in clinical studies as a result of infusion of the parenteral fluid were water weight gain, edema, increase in BUN, and dilutional hyponatremia. Asterixis was reported to have worsened in one patient during infusion of the amino acid solution.
Reactions which may occur because of the solution or the technique of administration include febrile response, infection at the site of injection, venous thrombosis or phlebitis extending from the site of injection, extravasation and hypervolemia.
Symptoms may result from an excess or deficit of one or more of the ions present in the solution; therefore, frequent monitoring of electrolyte levels is essential.
Phosphorus deficiency may lead to impaired tissue oxygenation and acute hemolytic anemia. Relative to calcium, excessive phosphorus intake can precipitate hypocalcemia with cramps, tetany and muscular hyperexcitability.
If an adverse reaction does occur, discontinue the infusion, evaluate the patient, institute appropriate therapeutic countermeasures, and save the remainder of the fluid for examination if deemed necessary.
Read the entire FDA prescribing information for Aminosyn HF 8 (Amino Acid Injection Hepatic Formula)