Medical Editor: John P. Cunha, DO, FACOEP
Anadrol-50 (oxymetholone) is an anabolic steroid used to treat certain types of anemia (lack of red blood cells), including aplastic anemia, myelofibrosis, or hypoplastic anemia caused by chemotherapy. Anadrol-50 is available in generic form. Common side effects of Anadrol-50 include:
- trouble sleeping (insomnia), or
- breast swelling in men.
Women taking Anadrol-50 may develop male characteristics, which could be irreversible if treatment is continued. Tell your doctor if you notice increased acne, changes in menstrual periods, a hoarse or deepened voice, male pattern baldness or hair growth (such as on the chin or chest), an enlarged clitoris, or changes in your sex drive while taking Anadrol-50. Tell your doctor if you have serious side effects of Anadrol-50 including:
- mental/mood changes,
- swelling of the ankles or feet,
- unusual or rapid weight gain,
- trouble breathing,
- decreased or increased interest in sex, or
- new or worsening acne.
The recommended daily dose of Anadrol-50 in children and adults is 1-5 mg/kg body weight per day. The usual effective dose is 1-2 mg/kg/day but higher doses may be required, and the dose is individualized. Response is not often immediate, and three to six months should be given. Anadrol-50 may interact with blood thinners or oral insulin or diabetes medication. There may be other drugs that can interact with Anadrol-50. Tell your doctor about all your prescription and over-the-counter medications and supplements you are taking. Anadrol-50 must not be used during pregnancy due to the risk of harm to a fetus. It is recommended that women of childbearing age use birth control while taking this drug. It is not known whether this drug passes into breast milk. Due to the potential harm to a nursing infant, breastfeeding is not recommended.
Our Anadrol-50 (oxymetholone) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have a serious side effect such as:
- swelling, rapid weight gain;
- increased or ongoing erection of the penis;
- changes in skin color;
- urination problems; or
- nausea, vomiting, stomach pain, loss of appetite, and jaundice (yellowing of the skin or eyes).
Women receiving oxymetholone may develop male characteristics, which could be irreversible if treatment is continued. Call your doctor as soon as possible if you notice any of these side effects:
- changes in your menstrual periods;
- hoarse or deepened voice;
- male-pattern hair growth (such as on the chin or chest);
- male pattern baldness;
- enlarged clitoris; or
- increase or decrease in sex drive.
Less serious side effects may include:
- breast swelling in men;
- feeling restless or excited;
- sleep problems (insomnia); or
This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.
Read the entire detailed patient monograph for Anadrol-50 (Oxymetholone)
Hepatic: Cholestatic jaundice with, rarely, hepatic necrosis and death. Hepatocellular neoplasms and peliosis hepatis have been reported in association with long-term androgenic anabolic steroid therapy (see WARNINGS).
Prepubertal: Phallic enlargement and increased frequency of erections.
In Both Sexes
Increased or decreased libido.
CNS: Excitation, insomnia.
Leukemia has been observed in patients with aplastic anemia treated with oxymetholone. The role, if any, of oxymetholone is unclear because malignant transformation has been seen in patients with blood dyscrasias and leukemia has been reported in patients with aplastic anemia who have not been treated with oxymetholone.
Larynx: Deepening of the voice in women.
Skin: Acne (especially in women and prepubertal boys).
Body as a Whole: Chills.
Metabolic/Endocrine: Decreased glucose tolerance (see PRECAUTIONS), increased serum levels of low-density lipoproteins and decreased levels of high-density lipoproteins (see PRECAUTIONS, Laboratory Tests), increased creatine and creatinine excretion, increased serum levels of creatinine phosphokinase (CPK). Reversible changes in liver function tests also occur, including increased Bromsulphalein (BSP) retention and increases in serum bilirubin, glutamic-oxaloacetic transaminase (SGOT), and alkaline phosphatase.
Drug Abuse And Dependence
ANADROL Tablets is considered to be a controlled substance and is listed in Schedule III.
Read the entire FDA prescribing information for Anadrol-50 (Oxymetholone)