Anafranil vs. Tofranil

Are Anafranil and Tofranil the Same Thing?

Anafranil (clomipramine hydrochloride) and Tofranil (imipramine hydrochloride) are tricyclic antidepressants used to treat different conditions.

Anafranil is used to treat symptoms of obsessive-compulsive disorder (OCD) such as recurrent thoughts or feelings and repetitive actions.

Tofranil is used to treat symptoms of depression.

What Are Possible Side Effects of Anafranil?

Common side effects of Anafranil include:

Tell your doctor if you have unlikely but serious side effects of Anafranil including:

  • mental/mood changes (e.g., confusion, depression),
  • enlarged or painful breasts,
  • unwanted breast milk production,
  • irregular or painful menstrual periods,
  • muscle stiffness,
  • ringing in the ears,
  • shakiness (tremors), or
  • trouble urinating.

What Are Possible Side Effects of Tofranil?

Common side effects of Tofranil include:

  • dry mouth,
  • blurred vision,
  • headache,
  • drowsiness,
  • dizziness,
  • constipation,
  • nausea,
  • vomiting,
  • loss of appetite,
  • diarrhea,
  • stomach cramps,
  • weight gain/loss,
  • increased sweating,
  • tingly feeling,
  • weakness,
  • lack of coordination,
  • ringing in your ears,
  • breast swelling (in men or women),
  • decreased sex drive,
  • impotence, or
  • difficulty having an orgasm.

You may have suicidal thoughts while taking Tofranil, especially if you are younger than 24 years old. Tell your doctor if this occurs. Tell your doctor if you experience rare but very serious side effects of Tofranil including:

What Is Anafranil?

Anafranil (clomipramine hydrochloride) is a tricyclic antidepressant used to treat symptoms of obsessive-compulsive disorder (OCD) such as recurrent thoughts or feelings and repetitive actions.

What Is Tofranil?

Tofranil (imipramine hydrochloride) is a tricyclic antidepressant used to treat symptoms of depression. Tofranil is available in generic form.

SLIDESHOW

Learn to Spot Depression: Symptoms, Warning Signs, Medication See Slideshow

What Drugs Interact With Anafranil?

Anafranil may interact with SSRI antidepressants, cimetidine, guanethidine, methylphenidate, phenytoin, warfarin, heart or blood pressure medications, heart rhythm medications, or anti-psychotic medications. Many other drugs can interact with Anafranil.

What Drugs Interact With Tofranil?

Tofranil may interact with SSRI antidepressants, cimetidine, clonidine, guanethidine, methylphenidate, or heart rhythm medications. Many other medications can interact with Tofranil. Tell your doctor all medications you use. Tofranil should be used only when prescribed during pregnancy. Infants born to mothers who have taken similar medications during pregnancy may have trouble urinating, prolonged sleepiness, shaking, and seizures. Consult your doctor. This medication passes into breast milk and may have undesirable effects on a nursing infant. Consult your doctor before breastfeeding.

How Should Anafranil Be Taken?

The adult starting dose of Anafranil is 25 mg daily and gradually increased, as tolerated, to approximately 100 mg during the first 2 weeks. Maximum dose is 250 mg daily. Consult your doctor for pediatric or adolescent dosing.

How Should Tofranil Be Taken?

For outpatient adults, the initial dose of Tofranil is 75 mg/day, increased to 150 mg/day. Dosages over 200 mg/day are not recommended. Dose may vary for adolescent, geriatric, childhood, or hospitalized patients.

QUESTION

Depression is a(n) __________ . See Answer
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References
SOURCE:

DailyMed. Anafranil Product Information.

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=4074b555-7635-41a9-809d-fae3b3610059&audience=consumer

DailyMed. Tofranil Product Information.

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=93b19ae0-c0a1-4400-9a56-6827939b7e7a

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