Medical Editor: John P. Cunha, DO, FACOEP
Androxy (fluoxymesterone tablets) is a synthetic androgen indicated for replacement therapy in conditions associated with a deficiency or absence of endogenous testosterone, such as primary hypogonadism (congenital or acquired), hypogonadotropic hypogonadism (congenital or acquired), delayed puberty, and in women, metastatic mammary cancer. Common side effects of Androxy include:
- excess hair growth
- male pattern baldness
- electrolyte imbalance
- yellowing of skin and eyes (jaundice)
- alterations in liver function tests
- increased or decreased libido
- numbness and tingling
- breast enlargement and prolonged erections in men, and in women
- menstrual irregularities
- inhibition of gonadotropin secretion
- deepening of the voice, and
- clitoral enlargement
Dosage and duration of therapy with Androxy will depend on age, sex, diagnosis, patient's response to treatment, and appearance of adverse effects. Androxy may interact with oral anticoagulants, antidiabetic drugs and insulin, ACTH and corticosteroids, and oxyphenbutazone. Tell your doctor all medications and supplements you use. Androxy is not recommended for use during pregnancy or breastfeeding. Consult your doctor.
Our Androxy (fluoxymesterone tablets) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Endocrine And Urogenital
The most common side effects of androgen therapy are amenorrhea and other menstrual irregularities, inhibition of gonadotropin secretion, and virilization, including deepening of the voice and clitoral enlargement. The latter usually is not reversible after androgens are discontinued. When administered to a pregnant woman, androgens cause virilization of external genitalia of the female fetus.
Gynecomastia, and excessive frequency and duration of penile erections. Oligospermia may occur at high dosages (see CLINICAL PHARMACOLOGY).
Skin and Appendages - Hirsutism, male pattern baldness, and acne.
Fluid and Electrolyte Disturbances - Retention of sodium, chloride, water, potassium, calcium (see WARNINGS), and inorganic phosphates.
Gastrointestinal - Nausea, cholestatic jaundice, alterations in liver function tests; rarely, hepatocellular neoplasms, peliosis hepatis, hepatic coma, and death (see WARNINGS).
Hematologic - Suppression of clotting factors II, V, VII, and X; bleeding in patients on concomitant anticoagulant therapy; and polycythemia.
Nervous System - Increased or decreased libido, headache, anxiety, depression, and generalized paresthesia.
Metabolic - Increased serum cholesterol.
Miscellaneous - Hypersensitivity; rarely, anaphylactoid reactions.
Read the entire FDA prescribing information for Androxy (Fluoxymesterone Tablets)