Definition of Angioimmunoblastic T-Cell Lymphoma (AITL)

Reviewed on 7/19/2021

Angioimmunoblastic T-cell lymphoma (AITL) is a rare form of non-Hodgkin lymphoma, which is a group of related cancers of the lymphatic system (lymphomas). Lymphomas are cancers of white blood cells (lymphocytes) that also function as part of the immune system. Signs and symptoms can include enlargement of a specific lymph node region or areas of lymph nodes as well as the presence of cancerous lymphocytes in other lymphatic tissues, such as the spleen and bone marrow. Spread, or metastases, to other body tissues and organs can occur. The exact cause of AITL is not fully understood.

Other associated symptoms of AITL can include rash, fever, unintentional weight loss, and tissue swelling. This type of cancer can cause dysfunction of the immune system, which can cause infections and other symptoms.

AITL is also known as angioimmunoblastic lymphadenopathy with dysproteinemia, AILD, immunoblastic lymphadenopathy, or lymphogranulomatosis X.

References
"Angioimmunoblastic T-Cell Lymphoma." National Organization for Rare Disorders. <https://rarediseases.org/rare-diseases/angioimmunoblastic-t-cell-lymphoma/>.

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