Ansaid Side Effects Center

Last updated on RxList: 8/2/2022
Ansaid Side Effects Center

What Is Ansaid?

Ansaid (flurbiprofen) is a nonsteroidal anti-inflammatory drug (NSAID) used to treat pain or inflammation caused by arthritis. Ansaid is available in generic form.

What Are Side Effects of Ansaid?

Common side effects of Ansaid include:

  • upset stomach,
  • stomach pain,
  • constipation,
  • diarrhea,
  • gas,
  • bloating,
  • heartburn,
  • nausea,
  • vomiting,
  • dizziness,
  • drowsiness,
  • fatigue,
  • headache,
  • nervousness,
  • skin itching or rash,
  • dry mouth,
  • increased sweating,
  • runny nose,
  • blurred vision, or
  • ringing in your ears.

Tell your doctor if you have unlikely but serious side effects of Ansaid including:

  • swelling of the hands or feet,
  • sudden or unexplained weight gain,
  • vision changes,
  • mental/mood changes,
  • fast or pounding heartbeat,
  • persistent or severe headache,
  • fainting,
  • difficult or painful swallowing, or
  • unusual tiredness.

Ansaid may cause serious side effects including:

  • hives,
  • difficulty breathing,
  • swelling of your face, lips, tongue, or throat,
  • sneezing,
  • wheezing,
  • chest pain spreading to your jaw or shoulder,
  • sudden numbness or weakness on one side of the body,
  • slurred speech,
  • shortness of breath,
  • vision changes,
  • skin rash (no matter how mild),
  • swelling or rapid weight gain,
  • bloody or tarry stools,
  • coughing up blood,
  • vomit that looks like coffee grounds,
  • nausea,
  • upper stomach pain,
  • itching,
  • tired feeling,
  • loss of appetite,
  • flu-like symptoms,
  • dark urine,
  • clay-colored stools,
  • yellowing of the skin or eyes (jaundice),
  • little or no urinating,
  • painful or difficult urination,
  • swelling in your feet or ankles,
  • tiredness,
  • pale skin,
  • lightheadedness,
  • rapid heart rate,
  • trouble concentrating,
  • fever,
  • sore throat,
  • burning in your eyes, and
  • skin pain followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling

Get medical help right away, if you have any of the symptoms listed above.

Seek medical care or call 911 at once if you have the following serious side effects:

  • Serious eye symptoms such as sudden vision loss, blurred vision, tunnel vision, eye pain or swelling, or seeing halos around lights;
  • Serious heart symptoms such as fast, irregular, or pounding heartbeats; fluttering in your chest; shortness of breath; and sudden dizziness, lightheartedness, or passing out;
  • Severe headache, confusion, slurred speech, arm or leg weakness, trouble walking, loss of coordination, feeling unsteady, very stiff muscles, high fever, profuse sweating, or tremors.

This document does not contain all possible side effects and others may occur. Check with your physician for additional information about side effects.

Dosage for Ansaid

To treat signs and symptoms of rheumatoid arthritis or osteoarthritis, the recommended starting dose of Ansaid is 200 to 300 mg per day, divided into doses two, three, or four times a day. The largest recommended single dose in a multiple-dose daily regimen is 100 mg.

What Drugs, Substances, or Supplements Interact with Ansaid?

Ansaid may interact with blood thinners, diuretics (water pills), cyclosporine, lithium, methotrexate, steroids, aspirin or NSAIDs, ACE inhibitors, or beta-blockers. Tell your doctor all medications you use.

Ansaid During Pregnancy and Breastfeeding

Ansaid should be used only when prescribed during the first 6 months of pregnancy. It is not recommended for use during the last 3 months of pregnancy due to possible harm to a fetus and interference with normal labor/delivery. This drug passes into breast milk and may have undesirable effects on a nursing infant. Consult your doctor before breastfeeding.

Additional Information

Our Ansaid (flurbiprofen) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

QUESTION

What joints are most often affected by osteoarthritis? See Answer
Ansaid Consumer Information

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Get emergency medical help if you have signs of an allergic reaction (sneezing, runny or stuffy nose, hives, wheezing or trouble breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling).

Get emergency medical help if you have signs of a heart attack or stroke: chest pain spreading to your jaw or shoulder, sudden numbness or weakness on one side of the body, slurred speech, feeling short of breath.

Stop using flurbiprofen and call your doctor at once if you have:

  • changes in your vision;
  • a skin rash, no matter how mild;
  • shortness of breath (even with mild exertion);
  • swelling or rapid weight gain;
  • signs of stomach bleeding--bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds;
  • liver problems--loss of appetite, stomach pain (upper right side), tiredness, itching, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
  • kidney problems--little or no urination, swelling in your feet or ankles, feeling tired or short of breath; or
  • low red blood cells (anemia)--pale skin, unusual tiredness, feeling light-headed or short of breath, cold hands and feet.

Common side effects may include:

  • indigestion, stomach pain, nausea, vomiting;
  • confusion, tremors, feeling nervous;
  • diarrhea, constipation;
  • headache, dizziness, drowsiness;
  • increased sweating, itching or rash; or
  • ringing in your ears.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

SLIDESHOW

Slideshow: Exercises for Knee Osteoarthritis and Joint Pain See Slideshow
Ansaid Professional Information

SIDE EFFECTS

TABLE 2: Reported adverse events in patients receiving ANSAID (flurbiprofen) or other nonsteroidal anti-inflammatory drugs

Reported in patients treated with ANSAID Reported in patients treated with other products but not ANSAID
Incidence of 1% or greater † Incidence < 1% - Causal Relationship Probable ‡ Incidence < 1% - Causal Relationship Unknown ‡
BODY AS A WHOLE
  edema
anaphylactic reaction
chills
fever
  < 1%:
  death
  infection
  sepsis
CARDIOVASCULAR SYSTEM congestive heart failure
hypertension
vascular diseases
vasodilation
angina pectoris
arrhythmias
myocardial infarction
< 1%:
  hypotension
  palpitations
  syncope
  tachycardia
  vasculitis
DIGESTIVE SYSTEM
  abdominal pain
  constipation
  diarrhea
  dyspepsia/heartburn
  elevated liver enzymes
  flatulence
  GI bleeding
  nausea
  vomiting
bloody diarrhea
esophageal disease
gastric/peptic ulcer
  disease
gastritis
jaundice (cholestatic and
noncholestatic)
hematemesis
hepatitis
stomatitis/glossitis
appetite changes
cholecystitis
colitis
dry mouth
exacerbation of
  inflammatory
bowel disease
periodontal abscess
small intestine
  inflammation with loss of
  blood and protein
> 1%:
  GI perforation
  GI ulcers
  (gastric/duodenal)
< 1%:
  eructation
  liver failure
  pancreatitis
HEMIC AND LYMPHATIC SYSTEM aplastic anemia
  (including
agranulocytosis or
pancytopenia)
decrease in hemoglobin
  and hematocrit
ecchymosis/purpura
eosinophilia
hemolytic anemia
iron deficiency anemia
leukopenia
thrombocytopenia
lymphadenopathy > 1%:
  anemia
  increased bleeding time
< 1%:
  melena
  rectal bleeding
METABOLIC AND NUTRITIONAL SYSTEM
  body weight changes
hyperuricemia hyperkalemia < 1%:
  hyperglycemia
NERVOUS SYSTEM
  headache
  nervousness and other  manifestations of entral nervous system   (CNS) stimulation (eg, anxiety, insomnia, increased reflexes,  tremor)
  symptoms associated   with CNS inhibition (eg, amnesia, asthenia, depression,
malaise, somnolence)
ataxia
cerebrovascular
  ischemia
confusion
paresthesia
twitching
convulsion
cerebrovascular accident
emotional lability
hypertonia
meningitis
myasthenia
subarachnoid hemorrhage
< 1%:
  coma
  dream abnormalities
  drowsiness
  hallucinations
RESPIRATORY SYSTEM
  rhinitis
asthma
epistaxis
bronchitis
dyspnea
hyperventilation
laryngitis
pulmonary embolism
pulmonary infarct
< 1%:
  pneumonia
  respiratory depression
SKIN AND APPENDAGES
  rash
angioedema
eczema
exfoliative dermatitis
photosensitivity
pruritus
toxic epidermal
necrolysis
urticaria
alopecia
dry skin
herpes simplex/zoster
nail disorder
sweating
< 1%:
  erythema multiforme
  Stevens Johnson
  syndrome
SPECIAL SENSES
  changes in vision
  dizziness/vertigo
  tinnitus
conjunctivitis
parosmia
changes in taste
corneal opacity
ear disease
glaucoma
retinal hemorrhage
retrobulbar neuritis
transient hearing loss
> 1%:
  pruritus
< 1%:
  hearing impairment
UROGENITAL SYSTEM
  signs and symptoms
  suggesting urinary tract infection
hematuria
interstitial nephritis
renal failure
menstrual disturbances
prostate disease
vaginal and uterine
  hemorrhage
vulvovaginitis
> 1%:
  abnormal renal function
< 1%:
  dysuria
  oliguria
  polyuria
  proteinuria
† from clinical trials
‡ from clinical trials, post-marketing surveillance, or literature

Read the entire FDA prescribing information for Ansaid (Flurbiprofen)

© Ansaid Patient Information is supplied by Cerner Multum, Inc. and Ansaid Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.

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