How Do Antimicrotubular Antineoplastics Work?

Reviewed on 10/25/2021

HOW DO ANTIMICROTUBULAR ANTINEOPLASTICS WORK?

Antimicrotubular antineoplastics are a class of drugs used to treat various cancers including breast, lung, stomach, ovarian, and pancreatic cancers. They are also used in the treatment of Hodgkin’s lymphoma (cancer that starts in white blood cells called lymphocytes), systemic anaplastic large cell lymphoma (a rare type of non-Hodgkin’s lymphoma), peripheral T-cell lymphoma (a diverse group of aggressive lymphomas that develop from mature-stage white blood cells called T cells and natural killer cells), primary cutaneous anaplastic large cell lymphoma (a subtype of cutaneous T-cell lymphoma), and CD30-expressing mycosis fungoides (a rare form of T-cell lymphoma of the skin).

Antimicrotubular antineoplastics work in the following ways:

  • They belong to a class called "chemotherapy drugs" that work by slowing down or stopping the growth of cancer cells.
  • They are also called as"“microtubule dynamics inhibitors," categorized as anticancer medications that work by killing the cancer cells.
  • They block cell growth by stopping a natural process called mitosis (cell division).
  • In addition, they interfere with the microtubules (cellular structures that help move chromosomes during mitosis).

HOW ARE ANTIMICROTUBULAR ANTINEOPLASTICS USED?

Antimicrotubular antineoplastics are used to treat conditions such as:

SLIDESHOW

Skin Cancer Symptoms, Types, Images See Slideshow

WHAT ARE SIDE EFFECTS OF ANTIMICROTUBULAR ANTINEOPLASTICS?

Some of the common side effects include:

Other rare side effects include:

 

Information contained herein is not intended to cover all possible side effects, precautions, warnings, drug interactions, allergic reactions, or adverse effects. Check with your doctor or pharmacist to make sure these drugs do not cause any harm when you take them along with other medicines. Never stop taking your medication and never change your dose or frequency without consulting your doctor.

WHAT ARE NAMES OF ANTIMICROTUBULAR ANTINEOPLASTICS?

Generic and brand names of antimicrotubular antineoplastics include:

References
https://reference.medscape.com/drugs/antineoplastics-antimicrotubular

https://www.webmd.com/drugs/2/drug-92547/paclitaxel-protein-bound-intravenous/details

https://www.webmd.com/drugs/2/drug-156890/brentuximab-vedotin-intravenous/details

https://www.rxlist.com/jevtana-drug.htm#description

https://www.rxlist.com/adcetris-drug.htm

https://medlineplus.gov/druginfo/meds/a611009.html

https://www.cancer.gov/news-events/cancer-currents-blog/2020/enfortumab-vedotin-bladder-cancer-fda-approval

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