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Antisocial Personality Disorder (cont.)

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What are complications if antisocial personality disorder is not treated? What is the prognosis of antisocial personality disorder?

Some societal costs of antisocial personality disorder, like the suffering endured by victims of the crimes committed by people with this disorder, are clear. However, when people with ASPD are the charismatic leaders of religious cults, the devastation they can create is often not known unless and until a catastrophe occurs. The multiple murders orchestrated by Charles Manson and the mass suicide that occurred at the command of the Reverend Jim Jones in Guyana in 1978 are just two such examples.

Individuals who suffer from antisocial personality disorder have a higher risk of abusing alcohol and other drugs and repeatedly committing crimes. Imprisonment is a potential consequence. People with antisocial personality disorder are also vulnerable to mood problems, such as major depression, anxiety, and bipolar disorder; having other personality disorders, especially borderline (BPD) and narcissistic personality disorders; self-mutilation and other forms of self-harm, as well as dying from homicide, suicide, or accident.

Antisocial personality disorder tends to make the prognosis of virtually any other condition more problematic. Having antisocial personality disorder makes the treatment for problems of substance abuse or emotional or physical substance dependence more difficult. People who have both antisocial personality disorder and schizophrenia are less likely to comply with treatment programs and are more likely to remain institutionalized in a prison or a hospital. These risks become magnified if antisocial personality disorder is not treated. Statistics indicate that many people with antisocial personality disorder experience a remission of symptoms by the time they reach 50 years of age.

Where can people find more information on specialists who treat antisocial personality disorder?

To find information on specialists who treat ASPD, visit

National Alliance on Mental Illness

National Institute of Mental Health


American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition. Arlington, Virginia: American Psychiatric Association, 2013.

Armelius, B.A., and T.H. Andreassen. "Cognitive-Behavioral Treatment for Antisocial Behavior in Youth in Residential Treatment." Cochrane Database Systems Review 17.4 Oct. 2007: CD 005650.

Azrin, N.H., B. Donohue, G.A. Teichner, et al. "A controlled evaluation and description of individual-cognitive problem solving and family-behavior therapies in dually-diagnosed conduct disordered and substance-dependent youth." Journal of Child and Adolescent Substance Abuse 11 (2001): 1-43.

Barnow, S., I. Ulrich, H.J. Grabe, H.J. Freyberger, and C. Spitzer. "The Influence of Parental Drinking Behavior and Antisocial Personality Disorder on Adolescent Behavioural Problems: Results of the Greifswalder Family Study." Alcohol and Alcoholism Advance Access, Oxford University Press, 8/1/07.

Bienenfeld, D. "Personality Disorders." July 17, 2008. <>.

Blackburn, R., and J.M. Lee-Evans. "Reactions of Primary and Secondary Psychopaths to Anger-Evoking Situations." British Journal of Clinical Psychology 24.2 May 1985: 93-100.

Blair, RJR. "Neurobiological Basis of Psychopathy." The British Journal of Psychiatry 182 (2003): 5-7.

Caldwell, M., J. Skeem, R. Salekin, and G.V. Rubroek. "Treatment Response of Adolescent Offenders With Psychopathy Features." Criminal Justice and Behavior 33.5 (2006): 571-596.

Caspi, A., J. McClay, T.E. Moffitt, J. Mill, J. Martin, I.W. Craig, A. Taylor, and R. Poulton. "Role of Genotype in the Cycle of Violence in Maltreated Children." Science 297.5582 Aug. 2, 2002: 851-854.

Compton, W.M., L.B. Cottler, J.L. Jacobs, A. Ben-Abdallah, and E.L. Spitznagel. "The Role of Psychiatric Disorders in Predicting Drug Dependence Treatment Outcomes." American Journal of Psychiatry 160 May 2003: 890-895.

Deeley, Q., E. Daly, S. Surguladze, N. Tunstall, G. Mezey, D. Beer, A. Ambikapathy, et al. "Facial Emotion Processing in Criminal Psychopathy. Preliminary Functional Magnetic Resonance Imaging Study." British Journal of Psychiatry 189 Dec. 2006: 533-539.

Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Treatment Revision. Washington, D.C.: American Psychiatric Association, 2000.

Dolan, M., and G. Davies. "Psychopathy and Institutional Outcome in Patients With Schizophrenia in Forensic Settings n the U.K." Schizophrenia Research 81.2-3 (2003): 277-281.

Foulks, E.F. "Commentary: Racial Bias in Diagnosis and Medication of Mentally Ill Minorities in Prisons and Communities." Journal of the American Academy of Psychiatry and the Law 32 (2004): 34-35.

Grekin, E.R., P.A. Brennan, S. Hodgins, and S.A. Mednick. "Male Criminals With Organic Brain Syndrome: Two Distinct Types Based on Age at First Arrest." American Journal of Psychiatry 158 July 2001: 1099-1104.

Harris, G.T., and M.E. Rice. "What Treatment Should Psychopaths Receive?" Cross Currents Spring 2006.

Hirstein, W. "What Is a Psychopath?" Psychology Today January 2013.

Liu, J. "Early health risk factors for violence: conceptualization, review of the evidence and implications." Aggressive Violent Behavior 16.1 (2011): 63-73.

Luntz, B.K., and C.S. Widom. "Antisocial Personality Disorder in Abused and Neglected Children Grown Up." American Journal of Psychiatry 151. 5 May 1994: 670-674.

Martens, W.H.J. "Antisocial and Psychopathic Personality Disorders: Causes, Course and Remission- A Review Article." International Journal of Offender Therapy and Comparative Criminology 44.4 (2000): 406-430.

Ogloff, J.R.P. "Psychopathy/Antisocial Personality Disorder Conundrum." Wiley Interscience Nov. 2005.

Pearson, C. "A Psychopath Unplugged." Neurological Correlates Mar. 19, 2008.

Simonoff, E., J. Elander, J. Holmshaw, A. Pickles, et al. "Predictors of Antisocial Personality: Continuities From Childhood to Adult Life." The British Journal of Psychiatry 184 (2004): 118-127.

Sjoberg, R.L., F. Ducci, C.S. Barr, T.K. Newman, L. Dell'Osso, M. Virkkunen, and D. Goldman. "A Non-additive Interaction of a Functional MAO-A VNTR and Testosterone Predicts Antisocial Behavior." Neuropsychopharmacology 33 (2008): 425-430.

Verona, E., J. Sprague, and S. Javdani. "Gender and factor-level interactions in psychopathy: Implications for self-directed violence risk and borderline personality disorder symptoms." Personality Disorders: Theory, Research, and Treatment 3.3 July 2012: 247-262.

Virkkunen, M. "Self-mutilation in Antisocial Personality (Disorder). Acta Psychiatrica Scandinavica 54.5 Aug. 23, 2007: 347-352.

Westen, D., and J. Harnden-Fischer. "Personality Profiles in Eating Disorders: Rethinking the Distinction Between Axis I and Axis II." American Journal of Psychiatry 158 Apr. 2001: 547-562.

Medically Reviewed by a Doctor on 2/16/2016


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