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Antizol

Last reviewed on RxList: 1/2/2018
Antizol Side Effects Center

Last reviewed on RxList 1/2/2018

Antizol (fomepizole) is an antidote used to treat poisoning with ethylene glycol (antifreeze) or methanol (contained in solvents, fuels, and other household or automotive chemicals). Antizol is sometimes used together with hemodialysis to rid the body of a poison. Antizol is available in generic form. Common side effects of Antizol include mild skin rash, heartburn, nausea, vomiting, diarrhea, loss of appetite, dizziness, drowsiness, anxiety, headache, metallic taste in mouth, hangover feeling, back pain, sore throat, ringing in ears, or changes in vision, changes in smell or taste senses.

Antizol is administered in a clinical setting and dose is determined by a physician. Antizol may interact with phenytoin, carbamazepine, cimetidine, or ketoconazole. Tell your doctor all medications and supplements you use. Antizol may be harmful to a fetus and is not recommended in pregnant women unless prescribed. It is unknown if this drug passes into breast milk or if it could harm a nursing baby. In a poisoning situation, it may not be possible to tell your caregivers that you are pregnant or breastfeeding before you are treated with Antizol. Make sure any doctor caring for your pregnancy or your baby knows you have received the medication.

Our Antizol (fomepizole) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

QUESTION

About how much does an adult human brain weigh? See Answer
Antizol Consumer Information

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Tell your caregiver right away if you have:

  • skin rash, bruising, severe tingling, numbness, pain, muscle weakness.
  • severe nausea, severe dizziness or spinning sensation; or
  • a light-headed feeling, like you might pass out.

Common side effects may include:

  • headache;
  • dizziness, drowsiness;
  • nausea; or
  • unpleasant or metallic taste in your mouth.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Read the entire detailed patient monograph for Antizol (Fomepizole)

SLIDESHOW

Digestive Disorders: Common Misconceptions See Slideshow
Antizol Professional Information

SIDE EFFECTS

The most frequent adverse events reported as drug-related or unknown relationship to study drug in the 78 patients and 63 normal volunteers who received Antizol® (fomepizole) Injection were headache (14%), nausea (11%), and dizziness, increased drowsiness, and bad taste/metallic taste (6% each). All other adverse events in this population were reported in approximately 3% or fewer of those receiving Antizol (fomepizole) and were as follows:

Body as a Whole: Abdominal pain, fever, multiorgan system failure, pain during Antizol (fomepizole) injection, inflammation at injection site, lumbalgia/backache, hangover

Cardiovascular: Sinus bradycardia/bradycardia, phlebosclerosis, tachycardia, phlebitis, shock, hypotension

Gastrointestinal: Vomiting, diarrhea, dyspepsia, heartburn, decreased appetite, transient transaminitis

Hemic/Lymphatic: Eosinophilia/hypereosinophilia, lymphangitis, disseminated intravascular coagulation, anemia

Nervous: Lightheadedness, seizure, agitation, feeling drunk, facial flush, vertigo, nystagmus, anxiety, "felt strange", decreased environmental awareness

Respiratory: Hiccups, pharyngitis

Skin/Appendages: Application site reaction, rash

Special Senses: Abnormal smell, speech/visual disturbances, transient blurred vision, roar in ear

Urogenital: Anuria

Read the entire FDA prescribing information for Antizol (Fomepizole)

Related Resources for Antizol

© Antizol Patient Information is supplied by Cerner Multum, Inc. and Antizol Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.

QUESTION

About how much does an adult human brain weigh? See Answer

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