Anusol Hc Side Effects Center

Last updated on RxList: 7/19/2022
Anusol Hc Side Effects Center

What Is Anusol-HC?

Anusol-HC (hydrocortisone acetate rectal suppositories, 25 mg) is a corticosteroid indicated for use in inflamed hemorrhoids, post-irradiation (factitial) proctitis, as an adjunct in the treatment of chronic ulcerative colitis, cryptitis, other inflammatory conditions of the anorectum, and anal itching (pruritis ani). Anusol-HC is available in generic form.

What Are Side Effects of Anusol-HC?

Common side effects of Anusol-HC include:

  • Application site reactions (rectal pain, redness, burning, itching, irritation, dryness)
  • Acne
  • Changes in menstrual periods
  • Increased sweating
  • Increased facial or body hair growth
  • Inflammation of hair follicles (folliculitis)
  • Lightening of skin color
  • Allergic skin rash
  • Secondary infection

Seek medical care or call 911 at once if you have the following serious side effects:

  • Serious eye symptoms such as sudden vision loss, blurred vision, tunnel vision, eye pain or swelling, or seeing halos around lights;
  • Serious heart symptoms such as fast, irregular, or pounding heartbeats; fluttering in your chest; shortness of breath; and sudden dizziness, lightheartedness, or passing out;
  • Severe headache, confusion, slurred speech, arm or leg weakness, trouble walking, loss of coordination, feeling unsteady, very stiff muscles, high fever, profuse sweating, or tremors.

This document does not contain all possible side effects and others may occur. Check with your physician for additional information about side effects.

Dosage for Anusol-HC?

The usual dosage of Anusol-HC is one suppository in the rectum morning and night for two weeks, in nonspecific proctitis. In more severe cases, one suppository three times daily; or two suppositories twice daily.

What Drugs, Substances, or Supplements Interact with Anusol-HC?

Anusol-HC may interact with other drugs. Tell your doctor all medications and supplements you use.

Anusol-HC During Pregnancy and Breastfeeding

During pregnancy, Anusol-HC should be used only if prescribed. Corticosteroids such as Anusol-HC should not be used extensively on pregnant patients, in large amounts, or for prolonged periods of time. It is unknown if Anusol-HC passes into breast milk. Breastfeeding while using Anusol-HC is not recommended.

Additional Information

Our Anusol-HC (hydrocortisone acetate rectal suppositories, 25 mg) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


Digestive Disorders: Common Misconceptions See Slideshow
Anusol Hc Consumer Information

3 pharmacies near 20147 have coupons for Anucort-HC (Brand Names:Anusol Hc for 120ML of 1%)

Wegmans Food Markets Inc
Wegmans Food Markets Inc

Est. Regular Price


with free coupon

View Coupon

Est. Regular Price


with free coupon

View Coupon
Harris Teeter Pharmacy
Harris Teeter Pharmacy

Est. Regular Price


with free coupon

View Coupon

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • severe rectal pain or burning, bleeding from your rectum;
  • new or worsening rectal irritation;
  • fever or other signs of infection; or
  • severe headaches, ringing in your ears, pain behind your eyes.

Common side effects may include:

  • rectal itching, burning, or other irritation; or
  • dryness or skin changes around the rectum.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Read the entire detailed patient monograph for Anusol Hc (Hydrocortisone Cream)


About how much does an adult human brain weigh? See Answer
Anusol Hc Professional Information


The following local adverse reactions are reported infrequently with topical corticosteroids, but may occur more frequently with the use of occlusive dressings. These reactions are listed in an approximate decreasing order of occurrence:

Acneiform eruptions
Perioral dermatitis
Allergic contact dermatitis
Maceration of the skin
Secondary infection
Skin atrophy

Read the entire FDA prescribing information for Anusol Hc (Hydrocortisone Cream)

© Anusol Hc Patient Information is supplied by Cerner Multum, Inc. and Anusol Hc Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.

Health Solutions From Our Sponsors