Medical Editor: John P. Cunha, DO, FACOEP
Aramine (metaraminol bitartrate) is a sympathomimetic amine used to prevent and treat the acute hypotensive state occurring with spinal anesthesia. Aramine is also indicated as adjunctive treatment of hypotension due to hemorrhage, reactions to medications, surgical complications, and shock associated with brain damage due to trauma or tumor. The brand name Aramine is discontinued, but generic versions may be available. Common side effects of Aramine (metaraminol bitartrate) include headache, nausea, vomiting, anxiety, dizziness, or nervousness. Serious side effects of Aramine (metaraminol bitartrate) include fast or slow heartbeat (tachycardia or bradycardia), heart throbbing or pounding, heart ventricle rhythm problems, high blood pressure (hypertension), or trouble breathing.
The recommended dose of Aramine is 2 to 10 mg (0.2 to 1mL). Aramine may interact with digitalis, monoamine oxidase inhibitors (MAOIs), or tricyclic antidepressants. Tell your doctor all medications and supplements you use. During pregnancy, Aramine should be used only if prescribed. It is unknown if this drug passes into breast milk. Consult your doctor before breastfeeding.
Our Aramine (metaraminol bitartrate) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Abscess formation, tissue necrosis, or sloughing rarely may follow the use of ARAMINE (metaraminol) . In choosing the site of injection, it is important to avoid those areas recognized as not suitable for use of any pressor agent and to discontinue the infusion immediately if infiltration or thrombosis occurs. Although the physician may be forced by the urgent nature of the patient's condition to choose injection sites that are not recognized as suitable, he should, when possible, use the preferred areas of injection. The larger veins of the antecubital fossa or the thigh are preferred to veins in the dorsum of the hand or ankle veins, particularly in patients with peripheral vascular disease, diabetes mellitus, Buerger's disease, or conditions with coexistent hypercoagulability.
Read the entire FDA prescribing information for Aramine (Metaraminol)