Brand Names: Arranon
Generic Name: nelarabine
- What is nelarabine (Arranon)?
- What are the possible side effects of nelarabine (Arranon)?
- What is the most important information I should know about nelarabine (Arranon)?
- What should I discuss with my healthcare provider before receiving nelarabine (Arranon)?
- How is nelarabine given (Arranon)?
- What happens if I miss a dose (Arranon)?
- What happens if I overdose (Arranon)?
- What should I avoid while receiving nelarabine (Arranon)?
- What other drugs will affect nelarabine (Arranon)?
- Where can I get more information (Arranon)?
What is nelarabine (Arranon)?
Nelarabine is a cancer medicine that interferes with the growth and spread of cancer cells in the body.
Nelarabine may also be used for purposes not listed in this medication guide.
What are the possible side effects of nelarabine (Arranon)?
Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Nelarabine may cause serious side effects of the central nervous system. These symptoms may not go away even after you stop receiving nelarabine. Tell your doctor if you have:
- extreme drowsiness, confusion;
- loss of balance or coordination;
- problems with walking;
- numbness, weakness, or tingly feeling in your hands or feet;
- problems with buttoning clothes or picking up small items with your fingers;
- a seizure; or
- loss of movement in any part of your body.
Also call your doctor at once if you have:
- unexplained muscle pain, tenderness, or weakness;
- low blood cell counts--fever, chills, tiredness, mouth sores, skin sores, easy bruising, unusual bleeding, pale skin, cold hands and feet, feeling light-headed or short of breath; or
- signs of tumor cell breakdown--confusion, weakness, muscle cramps, nausea, vomiting, fast or slow heart rate, decreased urination, tingling in your hands and feet or around your mouth.
Common side effects may include:
- drowsiness (for several days after your injection);
- nausea, vomiting, diarrhea, constipation;
- numbness or tingling;
- headache, tiredness; or
- blurred vision.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What is the most important information I should know about nelarabine (Arranon)?
Nelarabine may cause serious side effects on your central nervous system. Call your doctor right away if you have severe drowsiness, numbness and tingling in your hands or feet, problems with walking, loss of balance or coordination, or trouble using your fingers.
Avoid getting pregnant while using nelarabine and for at least 3 months after your last dose.
What should I discuss with my healthcare provider before receiving nelarabine (Arranon)?
You should not be treated with nelarabine if you are allergic to it.
Tell your doctor if you have ever had:
- liver disease;
- kidney disease;
- a nervous system disorder; or
- prior chemotherapy or radiation treatment of your head, neck, or spinal cord.
You may need to have a negative pregnancy test before starting this treatment.
Do not use nelarabine if you are pregnant. It could harm the unborn baby. Use effective birth control to prevent pregnancy while you are using this medicine and for at least 3 months after your last dose.
A man receiving nelarabine should use a condom during treatment, and for at least 3 months after treatment ends.
You should not breast-feed while you are receiving nelarabine.
How is nelarabine given (Arranon)?
Nelarabine is given as an infusion into a vein. A healthcare provider will give you this injection.
This medicine must be given slowly, and the infusion can take up to 2 hours to complete.
Nelarabine can lower your blood cell counts. Your blood will need to be tested often. Your cancer treatments may be delayed based on the results.
What happens if I miss a dose (Arranon)?
Call your doctor for instructions if you miss an appointment for your nelarabine injection.
What happens if I overdose (Arranon)?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
Overdose symptoms may include severe forms of some of the side effects listed in this medication guide.
What should I avoid while receiving nelarabine (Arranon)?
Avoid driving or hazardous activity until you know how this medicine will affect you. Your reactions could be impaired.
Avoid being near people who are sick or have infections. Tell your doctor at once if you develop signs of infection.
This medicine can pass into body fluids (urine, feces, vomit). For at least 48 hours after you receive a dose, avoid allowing your body fluids to come into contact with your hands or other surfaces. Caregivers should wear rubber gloves while cleaning up a patient's body fluids, handling contaminated trash or laundry or changing diapers. Wash hands before and after removing gloves. Wash soiled clothing and linens separately from other laundry.
What other drugs will affect nelarabine (Arranon)?
Other drugs may affect nelarabine, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.
Where can I get more information (Arranon)?
Your doctor or pharmacist can provide more information about nelarabine.
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