Artane vs. Akineton

Are Artane and Akineton the Same Thing?

Artane (trihexyphenidyl) and Akineton (biperiden hydrochloride) are used to treat the stiffness, tremors, spasms, and poor muscle control of Parkinson's disease. Artane and Akineton are also used to treat and prevent the same muscular conditions when they are caused by certain drugs.

Artane and Akineton belong to different drug classes. Artane is an antispasmodic drug and Akineton is an anticholinergic antiparkinson agent.

Side effects of Artane and Akineton that are similar include dry mouth, drowsiness, dizziness, blurred vision, difficulty urinating/urinary retention, constipation, or decreased sweating.

Side effects of Artane that are different from Akineton include nervousness, large pupils, anxiety, flushing, or upset stomach.

Side effects of Akineton that are different from Artane include dry nose/throat, euphoria or disorientation, nausea, vomiting, agitation, disturbed behavior, difficult or painful urination, involuntary movements, slow heart rate, and a reduction in rapid eye movement (REM) sleep.

What Are Possible Side Effects of Artane?

Common side effects of Artane include:

  • dry mouth,
  • nervousness,
  • drowsiness,
  • dizziness,
  • large pupils,
  • blurred vision,
  • difficulty urinating,
  • constipation,
  • nervousness,
  • anxiety,
  • decreased sweating,
  • flushing, or
  • upset stomach.

What Are Possible Side Effects of Akineton?

Common side effects of Akineton include:

  • dry mouth/nose/throat,
  • blurred vision,
  • drowsiness,
  • euphoria or disorientation,
  • urinary retention,
  • dizziness when standing up,
  • constipation,
  • nausea,
  • vomiting,
  • agitation,
  • disturbed behavior,
  • decreased sweating,
  • difficult or painful urination,
  • involuntary movements,
  • slow heart rate, and
  • a reduction in rapid eye movement (REM) sleep.

What Is Artane?

Artane (trihexyphenidyl) is an antispasmodic drug used to treat the stiffness, tremors, spasms, and poor muscle control of Parkinson's disease. Artane is also used to treat and prevent the same muscular conditions when they are caused by certain drugs.

What Is Akineton?

Akineton (biperiden hydrochloride) Tablet is an anticholinergic antiparkinson agent used to treat the stiffness, tremors, spasms, and poor muscle control of Parkinson's disease. Akineton is also used to treat and prevent these same muscular conditions when they are caused by drugs such as chlorpromazine, fluphenazine, perphenazine, and others.

QUESTION

Parkinson's disease is only seen in people of advanced age. See Answer

What Drugs Interact With Artane?

Artane may interact with alcohol, tricyclic antidepressants, phenothiazines, thiothixene, chlorprothixene, antihistamines (often found in prescription and over-the-counter cold, allergy, and sleep medicines), quinidine, amantadine, digoxin, or haloperidol. Tell your doctor all medications and supplements you use. It is not known whether trihexyphenidyl will be harmful to an unborn baby. It is also not known whether this drug is excreted in human milk. Consult your doctor before breastfeeding.

What Drugs Interact With Akineton?

Akineton may interact with narcotic pain relievers, phenothiazines and other antipsychotic medications, tricyclic antidepressants, antiarrhythmics, or antihistamines. Tell your doctor all medications you are taking. Akineton should be given during pregnancy only if prescribed. It is not known whether this drug is passed in breast milk. Consult your doctor before breastfeeding.

How Should Artane Be Taken?

As initial therapy for parkinsonism, a dose of 1 mg of Artane in tablet or elixir form may be administered the first day.

How Should Akineton Be Taken?

The usual starting dose of Akineton to treat Parkinson's disease is one tablet taken orally three or four times daily. The dosage is individualized and may be increased to a maximum of 8 tablets (16 mg) per 24 hours. To treat drug-induced extrapyramidal symptoms, the dose is one tablet one to three times daily.

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References
SOURCE:

FDA. Artane Product Information.

https://www.accessdata.fda.gov/drugsatfda_docs/nda/2003/006773_S036_ARTANE.pdf

RxList. Akineton Product Information.

https://www.rxlist.com/akineton-side-effects-drug-center.htm

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