Slideshows Images Quizzes

Copyright © 2018 by RxList Inc. RxList does not provide medical advice, diagnosis or treatment. See additional information.

Artane vs. Gocovri

Reviewed on 1/28/2019

Are Artane and Gocovri the Same Thing?

Artane (trihexyphenidyl) and Gocovri (amantadine extended release capsules) are used to treat the stiffness, tremors, spasms, and poor muscle control of Parkinson's disease.

Artane is also used to treat and prevent the same muscular conditions when they are caused by certain drugs.

Artane and Gocovri belong to different drug classes. Artane is an antispasmodic drug and Gocovri is an antivirial medication.

Side effects of Artane and Gocovri that are similar include dry mouth, dizziness, blurred vision, constipation, or anxiety.

Side effects of Artane that are different from Gocovri include nervousness, drowsiness, large pupils, difficulty urinating, decreased sweating, flushing, or upset stomach.

Side effects of Gocovri that are different from Artane include hallucinations, dizziness, swelling of extremities, falls, dizziness on standing, insomnia, depression, abnormal dreams, confusion, headache, muscle cramps, nausea, vomiting, gait disturbance, bruising, urinary tract infection, changes in skin pigmentation, decreased appetite, cataracts, dry eyes, joint swelling, muscle spasms, benign prostatic hyperplasia (BPH), and cough.

What Are Possible Side Effects of Artane?

Common side effects of Artane include:

  • dry mouth,
  • nervousness,
  • drowsiness,
  • dizziness,
  • large pupils,
  • blurred vision,
  • difficulty urinating,
  • constipation,
  • nervousness,
  • anxiety,
  • decreased sweating,
  • flushing, or
  • upset stomach.

What Are Possible Side Effects of Gocovri?

Common side effects of Gocovri include:

  • hallucinations,
  • dizziness,
  • dry mouth,
  • swelling of extremities,
  • constipation,
  • falls,
  • and dizziness on standing (orthostatic hypotension).

Other side effects of Gocovri include:

  • anxiety,
  • insomnia,
  • depression,
  • abnormal dreams,
  • confusion,
  • headache,
  • muscle cramps,
  • nausea,
  • vomiting,
  • gait disturbance,
  • bruising,
  • urinary tract infection,
  • changes in skin pigmentation,
  • decreased appetite,
  • blurred vision,
  • cataracts,
  • dry eyes,
  • joint swelling,
  • muscle spasms,
  • benign prostatic hyperplasia (BPH),
  • and cough.

What Is Artane?

Artane (trihexyphenidyl) is an antispasmodic drug used to treat the stiffness, tremors, spasms, and poor muscle control of Parkinson's disease. Artane is also used to treat and prevent the same muscular conditions when they are caused by certain drugs.

What Is Gocovri?

Gocovri (amantadine extended release capsules) is an antivirial and anti-Parkinson drug indicated for the treatment of dyskinesia in patients with Parkinson's disease receiving levodopa-based therapy, with or without concomitant dopaminergic medications.

SLIDESHOW

Dementia, Alzheimer's Disease, and Aging Brains See Slideshow

What Drugs Interact With Artane?

Artane may interact with alcohol, tricyclic antidepressants, phenothiazines, thiothixene, chlorprothixene, antihistamines (often found in prescription and over-the-counter cold, allergy, and sleep medicines), quinidine, amantadine, digoxin, or haloperidol. Tell your doctor all medications and supplements you use. It is not known whether trihexyphenidyl will be harmful to an unborn baby. It is also not known whether this drug is excreted in human milk. Consult your doctor before breastfeeding.

What Drugs Interact With Gocovri?

Gocovri may interact with other anticholinergic drugs, carbonic anhydrase inhibitors, sodium bicarbonate, alcohol, and “live” vaccines. Tell your doctor all medications and supplements you use and all vaccines you recently received. Gocovri is not recommended for use during pregnancy; it may harm a fetus. Gocovri passes into breast milk but its effect on nursing infants is unknown. Gocovri may alter breast milk production or excretion. Consult your doctor before breastfeeding.

How Should Artane Be Taken?

As initial therapy for parkinsonism, a dose of 1 mg of Artane in tablet or elixir form may be administered the first day.

How Should Gocovri Be Taken?

The initial daily dosage of Gocovri is 137 mg, administered orally once daily at bedtime. After one week, increase to the recommended dosage of 274 mg (two 137 mg capsules) once daily at bedtime.

QUESTION

One of the first symptoms of Alzheimer's disease is __________________. See Answer
Disclaimer

All drug information provided on RxList.com is sourced directly from drug monographs published by the U.S. Food and Drug Administration (FDA).

Any drug information published on RxList.com regarding general drug information, drug side effects, drug usage, dosage, and more are sourced from the original drug documentation found in its FDA drug monograph.

Drug information found in the drug comparisons published on RxList.com is primarily sourced from the FDA drug information. The drug comparison information found in this article does not contain any data from clinical trials with human participants or animals performed by any of the drug manufacturers comparing the drugs.

The drug comparisons information provided does not cover every potential use, warning, drug interaction, side effect, or adverse or allergic reaction. RxList.com assumes no responsibility for any healthcare administered to a person based on the information found on this site.

As drug information can and will change at any time, RxList.com makes every effort to update its drug information. Due to the time-sensitive nature of drug information, RxList.com makes no guarantees that the information provided is the most current.

Any missing drug warnings or information does not in any way guarantee the safety, effectiveness, or the lack of adverse effects of any drug. The drug information provided is intended for reference only and should not be used as a substitute for medical advice.

If you have specific questions regarding a drug’s safety, side effects, usage, warnings, etc., you should contact your doctor or pharmacist, or refer to the individual drug monograph details found on the FDA.gov or RxList.com websites for more information.

You may also report negative side effects of prescription drugs to the FDA by visiting the FDA MedWatch website or calling 1-800-FDA-1088.

References
SOURCE:

FDA. Artane Product Information.

https://www.accessdata.fda.gov/drugsatfda_docs/nda/2003/006773_S036_ARTANE.pdf

Adamas Pharmaceuticals, Inc. Gocovri Product Information.

https://www.gocovri.com
CONTINUE SCROLLING FOR RELATED SLIDESHOW

Health Solutions From Our Sponsors