- Are Gocovri and Artane the Same Thing?
- What Are Possible Side Effects of Artane?
- What Are Possible Side Effects of Gocovri?
- What Is Artane?
- What Is Gocovri?
- What Drugs Interact with Artane?
- What Drugs Interact with Gocovri?
- How Should Artane Be Taken?
- How Should Gocovri Be Taken?
Are Artane and Gocovri the Same Thing?
Artane (trihexyphenidyl) and Gocovri (amantadine extended release capsules) are used to treat the stiffness, tremors, spasms, and poor muscle control of Parkinson's disease.
Artane is also used to treat and prevent the same muscular conditions when they are caused by certain drugs.
Artane and Gocovri belong to different drug classes. Artane is an antispasmodic drug and Gocovri is an antivirial medication.
Side effects of Artane and Gocovri that are similar include dry mouth, dizziness, blurred vision, constipation, or anxiety.
Side effects of Artane that are different from Gocovri include nervousness, drowsiness, large pupils, difficulty urinating, decreased sweating, flushing, or upset stomach.
Side effects of Gocovri that are different from Artane include hallucinations, dizziness, swelling of extremities, falls, dizziness on standing, insomnia, depression, abnormal dreams, confusion, headache, muscle cramps, nausea, vomiting, gait disturbance, bruising, urinary tract infection, changes in skin pigmentation, decreased appetite, cataracts, dry eyes, joint swelling, muscle spasms, benign prostatic hyperplasia (BPH), and cough.
What Are Possible Side Effects of Artane?
Common side effects of Artane include:
- dry mouth,
- large pupils,
- blurred vision,
- difficulty urinating,
- decreased sweating,
- flushing, or
- upset stomach.
What Are Possible Side Effects of Gocovri?
Common side effects of Gocovri include:
- dry mouth,
- swelling of extremities,
- and dizziness on standing (orthostatic hypotension).
Other side effects of Gocovri include:
- abnormal dreams,
- muscle cramps,
- gait disturbance,
- urinary tract infection,
- changes in skin pigmentation,
- decreased appetite,
- blurred vision,
- dry eyes,
- joint swelling,
- muscle spasms,
- benign prostatic hyperplasia (BPH),
- and cough.
What Is Artane?
Artane (trihexyphenidyl) is an antispasmodic drug used to treat the stiffness, tremors, spasms, and poor muscle control of Parkinson's disease. Artane is also used to treat and prevent the same muscular conditions when they are caused by certain drugs.
What Is Gocovri?
Gocovri (amantadine extended release capsules) is an antivirial and anti-Parkinson drug indicated for the treatment of dyskinesia in patients with Parkinson's disease receiving levodopa-based therapy, with or without concomitant dopaminergic medications.
What Drugs Interact With Artane?
Artane may interact with alcohol, tricyclic antidepressants, phenothiazines, thiothixene, chlorprothixene, antihistamines (often found in prescription and over-the-counter cold, allergy, and sleep medicines), quinidine, amantadine, digoxin, or haloperidol. Tell your doctor all medications and supplements you use. It is not known whether trihexyphenidyl will be harmful to an unborn baby. It is also not known whether this drug is excreted in human milk. Consult your doctor before breastfeeding.
What Drugs Interact With Gocovri?
Gocovri may interact with other anticholinergic drugs, carbonic anhydrase inhibitors, sodium bicarbonate, alcohol, and “live” vaccines. Tell your doctor all medications and supplements you use and all vaccines you recently received. Gocovri is not recommended for use during pregnancy; it may harm a fetus. Gocovri passes into breast milk but its effect on nursing infants is unknown. Gocovri may alter breast milk production or excretion. Consult your doctor before breastfeeding.
How Should Artane Be Taken?
As initial therapy for parkinsonism, a dose of 1 mg of Artane in tablet or elixir form may be administered the first day.
How Should Gocovri Be Taken?
The initial daily dosage of Gocovri is 137 mg, administered orally once daily at bedtime. After one week, increase to the recommended dosage of 274 mg (two 137 mg capsules) once daily at bedtime.
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FDA. Artane Product Information.
Adamas Pharmaceuticals, Inc. Gocovri Product Information.