Slideshows Images Quizzes

Copyright © 2018 by RxList Inc. RxList does not provide medical advice, diagnosis or treatment. See additional information.

Arthrotec vs. Toradol

Reviewed on 1/30/2019

Are Arthrotec and Toradol the Same Thing?

Arthrotec (diclofenac sodium/misoprostol) and Toradol (ketorolac tromethamine) are both used to treat different types of pain.

Arthrotec is used to treat osteoarthritis and rheumatoid arthritis in people at high risk for developing stomach or intestinal ulcers.

Toradol is used to treat moderately severe pain and inflammation, usually after surgery.

The brand name Toradol is no longer available in the U.S. Generic versions may be available.

Arthrotec and Toradol both contain a nonsteroidal anti-inflammatory drug (NSAID) and Arthrotec also contains a prostaglandin that protects the stomach from irritating effects of NSAIDs.

Side effects of Arthrotec and Toradol that are similar include diarrhea, upset stomach or stomach pain, nausea, bloating, gas, dizziness, drowsiness, headache, or ringing in the ears.

Side effects of Arthrotec that are different from Toradol include blurred vision or unusual vaginal bleeding.

Side effects of Toradol that are different from Arthrotec include heartburn, vomiting, constipation, or sweating.

What Are Possible Side Effects of Arthrotec?

Common side effects of Arthrotec include:

  • nausea,
  • bloating,
  • gas,
  • dizziness,
  • drowsiness,
  • headache,
  • blurred vision,
  • ringing in your ears, or
  • unusual vaginal bleeding.

Tell your doctor if you have serious side effects of Arthrotec including:

  • difficult or painful swallowing,
  • swelling of the hands or feet,
  • sudden or unexplained weight gain,
  • vision changes,
  • mental/mood changes (e.g., depression),
  • fast or pounding heartbeat,
  • persistent or severe headache,
  • fainting,
  • menstrual problems/irregular periods,
  • unusual tiredness,
  • easy bruising or bleeding,
  • signs of infection (e.g., fever, persistent sore throat),
  • changes in the amount of urine, or
  • unexplained stiff neck.

What Are Possible Side Effects of Toradol?

Common side effects of Toradol include:

  • heartburn,
  • stomach or abdominal pain,
  • upset stomach,
  • nausea,
  • diarrhea,
  • constipation,
  • bloating,
  • gas,
  • dizziness,
  • nervousness,
  • skin rash,
  • headache,
  • blurred vision,
  • ringing in your ears, and
  • itching.

What Is Arthrotec?

Arthrotec (diclofenac sodium/misoprostol) is a combination non-steroidal anti-inflammatory drug (NSAID) and a prostaglandin that protects the stomach from irritating effects of NSAIDs used to treat osteoarthritis and rheumatoid arthritis in people at high risk for developing stomach or intestinal ulcers. Arthrotec is available in generic form. Common side effects of Arthrotec include diarrhea and upset stomach or stomach pain within a few weeks after you start taking this medication, and usually last for about 1 week.

What Is Toradol?

Toradol (ketorolac tromethamine) is a nonsteroidal anti-inflammatory drug (NSAID) that is used to treat moderately severe pain and inflammation, usually after surgery. Toradol works by blocking the production of prostaglandins, compounds that cause pain, fever, and inflammation. The brand name Toradol is no longer available in the U.S. Generic versions may be available.

QUESTION

What joints are most often affected by osteoarthritis? See Answer

What Drugs Interact With Arthrotec?

Arthrotec may interact with blood thinners, cyclosporine, digoxin, diuretics (water pills), insulin or oral diabetes medicine, lithium, methotrexate, phenobarbital, steroids, aspirin or other NSAIDs, or ACE inhibitors. Tell your doctor all medications you use. Arthrotec must not be used during pregnancy. It can harm the fetus and mother. Use birth control while taking this medication. This medication passes into breast milk. However, this drug is unlikely to harm a nursing infant. Consult your doctor before breastfeeding.

What Drugs Interact With Toradol?

Drug interactions may occur with lithium, ACE inhibitors, warfarin, and medications used to treat high uric acid levels. Warnings may apply to individuals who have ulcers, cardiovascular disease, kidney disease, and bleeding disorders. People who are taking aspirin or NSAIDs should not take Toradol because of the cumulative risk of inducing serious NSAID-related side effects.

How Should Arthrotec Be Taken?

For the relief of rheumatoid arthritis and osteoarthritis, the recommended dose of Arthrotec is 50 mg diclofenac sodium/200 mcg misoprostol or 75 mg diclofenac sodium/200 mcg misoprostol.

How Should Toradol Be Taken?

Toradol is available as a 10 mg tablet and a solution (30 mg per ml) for intravenous (IV) or intramuscular (IM) administration. Toradol solution is administered as a single 15- to 60-mg dose once every 6 hours not to exceed 60 or 120 mg a day. The recommended oral dose is one to two Toradol tablets initially followed by one tablet every 4-6 hours, not to exceed 40 mg daily. Toradol should not be used for more than 5 days.

SLIDESHOW

Slideshow: Exercises for Knee Osteoarthritis and Joint Pain See Slideshow
Disclaimer

All drug information provided on RxList.com is sourced directly from drug monographs published by the U.S. Food and Drug Administration (FDA).

Any drug information published on RxList.com regarding general drug information, drug side effects, drug usage, dosage, and more are sourced from the original drug documentation found in its FDA drug monograph.

Drug information found in the drug comparisons published on RxList.com is primarily sourced from the FDA drug information. The drug comparison information found in this article does not contain any data from clinical trials with human participants or animals performed by any of the drug manufacturers comparing the drugs.

The drug comparisons information provided does not cover every potential use, warning, drug interaction, side effect, or adverse or allergic reaction. RxList.com assumes no responsibility for any healthcare administered to a person based on the information found on this site.

As drug information can and will change at any time, RxList.com makes every effort to update its drug information. Due to the time-sensitive nature of drug information, RxList.com makes no guarantees that the information provided is the most current.

Any missing drug warnings or information does not in any way guarantee the safety, effectiveness, or the lack of adverse effects of any drug. The drug information provided is intended for reference only and should not be used as a substitute for medical advice.

If you have specific questions regarding a drug’s safety, side effects, usage, warnings, etc., you should contact your doctor or pharmacist, or refer to the individual drug monograph details found on the FDA.gov or RxList.com websites for more information.

You may also report negative side effects of prescription drugs to the FDA by visiting the FDA MedWatch website or calling 1-800-FDA-1088.

References
SOURCE:

Pfizer. Arthrotec Product Information.

https://www.pfizermedicalinformation.com/en-us/arthrotec

Dailymed. Toradol Product Information.

https://www.accessdata.fda.gov/drugsatfda_docs/label/2013/019645s019lbl.pdf
CONTINUE SCROLLING FOR RELATED SLIDESHOW

Health Solutions From Our Sponsors