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Aspartates

What other names is Aspartates known by?

Acide Aspartique, Acide L-Aspartique, Asparatate Chelated Minerals, Aspartate Mineral Chelates, Aspartate de Potassium, Aspartatos, Aspartic Acid, D-Aspartic Acid, L-Aspartate, L-Aspartic Acid, Mineral Aspartates, N-Methyl-D-Aspartic Acid, Potassium Aspartate.

What is Aspartates?

Aspartate is a vitamin-like substance called an amino acid. As a dietary supplement, aspartate is combined with minerals and is available as copper aspartate, iron aspartate, magnesium aspartate, manganese aspartate, potassium aspartate, and zinc aspartate.

Aspartates are used to increase absorption of the minerals they are combined with and to enhance athletic performance. Some forms are used to reduce brain damage caused by cirrhosis of the liver (hepatic encephalopathy) when given intravenously by a healthcare professional.

Insufficient Evidence to Rate Effectiveness for...

  • Liver cirrhosis. Developing research suggests L-ornithine-L-aspartate given by IV (intravenously) might reduce brain damage in some patients with liver cirrhosis.
  • Enhancing athletic performance.
  • Increasing mineral levels. So far there is not evidence that aspartates increase mineral absorption. Except in cases of mineral deficiency, such as iron-deficiency anemia, a well-balanced diet typically provides the recommended daily allowance (RDA) of minerals.
  • Other conditions.
More evidence is needed to rate the effectiveness of aspartates for these uses.

QUESTION

Next to red peppers, you can get the most vitamin C from ________________. See Answer

How does Aspartates work?

There isn't enough information to know how aspartates work.

Are there safety concerns?

It is not known if aspartates are safe.

Special Precautions & Warnings:

Pregnancy and breast-feeding: Not enough is known about the use of aspartates during pregnancy and breast-feeding. Stay on the safe side and avoid use.

Dosing considerations for Aspartates.

The appropriate dose of aspartates depends on several factors such as the user's age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for aspartates. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.

Natural Medicines Comprehensive Database rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, and Insufficient Evidence to Rate (detailed description of each of the ratings).

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Reviewed on 9/17/2019
References

Abel, T., Knechtle, B., Perret, C., Eser, P., von Arx, P., and Knecht, H. Influence of chronic supplementation of arginine aspartate in endurance athletes on performance and substrate metabolism - a randomized, double-blind, placebo-controlled study. Int J Sports Med 2005;26(5):344-349. View abstract.

Colombani, P. C., Bitzi, R., Frey-Rindova, P., Frey, W., Arnold, M., Langhans, W., and Wenk, C. Chronic arginine aspartate supplementation in runners reduces total plasma amino acid level at rest and during a marathon run. Eur J Nutr. 1999;38(6):263-270. View abstract.

Denis, C., Dormois, D., Linossier, M. T., Eychenne, J. L., Hauseux, P., and Lacour, J. R. Effect of arginine aspartate on the exercise-induced hyperammoniemia in humans: a two periods cross-over trial. Arch.Int Physiol Biochim.Biophys. 1991;99(1):123-127. View abstract.

FORMICA, P. E. The housewife syndrome. Treatment with the potassium and magnesium salts of aspartic acid. Curr.Ther.Res.Clin.Exp. 1962;4:98-106. View abstract.

Franzoni, F., Mataloni, E., Femia, R., and Galetta, F. Effect of oral potassium supplementation on QT dispersion in anorexia nervosa. Acta Paediatr. 2002;91(6):653-656. View abstract.

HICKS, J. T. TREATMENT OF FATIGUE IN GENERAL PRACTICE: A DOUBLE BLIND STUDY. Clin.Med (Northfield.Il) 1964;71:85-90. View abstract.

Kirk, S. J., Hurson, M., Regan, M. C., Holt, D. R., Wasserkrug, H. L., and Barbul, A. Arginine stimulates wound healing and immune function in elderly human beings. Surgery 1993;114(2):155-159. View abstract.

NAGLE, F. J., BALKE, B., GANSLEN, R. V., and DAVIS, A. W., Jr. THE MITIGATION OF PHYSICAL FATIGUE WITH "SPARTASE". REP 63-12. Rep.Civ.Aeromed.Res.Inst.US. 1963;1-10. View abstract.

Ruddel, H., Werner, C., and Ising, H. Impact of magnesium supplementation on performance data in young swimmers. Magnes.Res 1990;3(2):103-107. View abstract.

SHAW, D. L., Jr., CHESNEY, M. A., TULLIS, I. F., and AGERSBORG, H. P. Management of fatigue: a physiologic approach. Am.J Med Sci. 1962;243:758-769. View abstract.

Trudeau, F. and Murphy, R. Effects of potassium-aspartate salt administration on glycogen use in the rat during a swimming stress. Physiol Behav. 1993;54(1):7-12. View abstract.

Trudeau, F. Aspartate and its ergogenic potential. Science & Sports 1996;11(4):223-232.

Tuttle, J. L., Potteiger, J. A., Evans, B. W., and Ozmun, J. C. Effect of acute potassium-magnesium aspartate supplementation on ammonia concentrations during and after resistance training. Int J Sport Nutr. 1995;5(2):102-109. View abstract.

Beltz SD, Doering PL. Efficacy of nutritional supplements used by athletes. Clin Pharm 1993;12:900-8. View abstract.

Firoz M, Graber M. Bioavailability of US commercial magnesium preparations. Magnes Res 2001;14:257-62.. View abstract.

Rees C, Oppong K, Mardini H, et al. Effect of L-Ornithine-L-Aspartate on patients with and without TIPS undergoing glutamine challenge: a double blind, placebo controlled trial. Gut 2000;47:571-4.. View abstract.

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Witteman JC, Grobbee DE, Derkx FH, et al. Reduction of blood pressure with oral magnesium supplementation in women with mild to moderate hypertension. Am J Clin Nutr 1994;60:129-35. View abstract.

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