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Aspirin vs. Acetaminophen (Tylenol)

Medical and Pharmacy Editor:

Are Aspirin and Acetaminophen (Tylenol) the Same Thing?

Aspirin is a nonsteroidal anti-inflammatory drug (NSAID) used to treat fever, pain.

Aspirin is also used to treat inflammation in the body, to prevent blood clots, and to reduce the risk of strokes and heart attacks.

Aspirin and Tylenol belong to different drug classes. Aspirin is a nonsteroidal anti-inflammatory drug (NSAID) and Tylenol is an analgesic (pain reliever) and antipyretic (fever reducer).

Brand names for aspirin include Bayer Aspirin, Ecotrin, and Bufferin.

What Are Possible Side Effects of Aspirin?

Common side effects of Aspirin include:

  • rash,
  • gastrointestinal ulcerations,
  • abdominal pain,
  • upset stomach,
  • heartburn,
  • drowsiness,
  • headache,
  • cramping,
  • nausea,
  • gastritis, and
  • bleeding

What Are Possible Side Effects of Acetaminophen (Tylenol)?

Common side effects of Acetaminophen (Tylenol) include:

  • nausea,
  • stomach pain,
  • loss of appetite,
  • itching,
  • rash,
  • headache,
  • dark urine,
  • clay-colored stools,
  • or jaundice (yellowing of skin or eyes).

Get medical help right away if you notice symptoms of a rare serious allergic reaction to Tylenol, including:

  • rash,
  • itching/swelling (especially of the face/tongue/throat),
  • severe dizziness,
  • or trouble breathing.

What is Aspirin?

Aspirin (aspirin) is a nonsteroidal anti-inflammatory drug (NSAID) prescribed for treating fever, pain, inflammation in the body, prevention of blood clots, and reduction of the risk of strokes and heart attacks.

What is Acetaminophen (Tylenol)?

Tylenol (acetaminophen) is an analgesic (pain reliever) and antipyretic (fever reducer) used for treating pain and fever associated with many conditions. Tylenol is available in generic form and over-the-counter (OTC).

What Drugs Interact With Aspirin?

Aspirin may interact with other blood thinners, aspirin, or nonsteroidal anti-inflammatory drugs (NSAIDs).

What Drugs Interact With Acetaminophen (Tylenol)?

Tylenol may interact with antibiotics, antifungals, sulfa drugs, tuberculosis medicines, birth control pills or hormone replacement therapy, blood pressure medication, cancer medications, cholesterol-lowering medications, gout or arthritis medications (including gold injections), HIV/AIDS medications, medicines to treat psychiatric disorders, nonsteroidal anti-inflammatory drugs (NSAIDs), or seizure medications.

How Should Aspirin Be Taken?

Bayer Aspirin dose ranges from 50 mg to 6000 mg daily.

How Should Acetaminophen (Tylenol) Be Taken?

The oral dose of Tylenol for adults is 325 to 650 mg every 4 to 6 hours. The maximum daily dose is 4 grams.

Reviewed on 9/5/2018

References:

Bayer. Aspirin Product Information.

https://www.bayeraspirin.com/

Johnson & Johnson Consumer Inc. Tylenol Product Information.

www.tylenol.com

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