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Aspirin vs. Ibuprofen (Advil, Motrin)

Are Aspirin and Ibuprofen (Advil, Motrin) the Same Thing?

Aspirin and ibuprofen are nonsteroidal anti-inflammatory drugs (NSAIDs) used to treat fever, pain, and inflammation in the body.

Aspirin is also used to prevent blood clots, and to reduce the risk of strokes and heart attacks.

Ibuprofen is also used to treat signs and symptoms of rheumatoid arthritis and osteoarthritis, and for treatment of menstrual cramps (primary dysmenorrhea).

Brand names for aspirin include Bayer Aspirin, Ecotrin, and Bufferin.

Brand names for ibuprofen include Motrin and Advil.

What Are Possible Side Effects of Aspirin?

Common side effects of Aspirin include:

What Are Possible Side Effects of Ibuprofen (Advil, Motrin)?

Common side effects of Ibuprofen (Advil, Motrin) include:

What Is Aspirin?

Aspirin (aspirin) is a nonsteroidal anti-inflammatory drug (NSAID) prescribed for treating fever, pain, inflammation in the body, prevention of blood clots, and reduction of the risk of strokes and heart attacks.

What Is Ibuprofen (Advil, Motrin)?

Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) indicated for relief of the signs and symptoms of rheumatoid arthritis and osteoarthritis, for relief of mild to moderate pain, and for treatment of primary dysmenorrhea. A generic formulation is available.


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What Drugs Interact With Aspirin?

Aspirin may interact with other blood thinners, aspirin, or nonsteroidal anti-inflammatory drugs (NSAIDs).

What Drugs Interact With Ibuprofen (Advil, Motrin)?

Ibuprofen may interact with other drugs. Tell your doctor all medications and supplements you use.

How Should Aspirin Be Taken?

Bayer Aspirin dose ranges from 50 mg to 6000 mg daily.

How Should Ibuprofen (Advil, Motrin) Be Taken?

The recommended dose of Motrin should be adjusted to suit individual patients needs but should not exceed 3200 mg in the total daily dose. Use of alcohol and smoking could increase side effects. Safe use of Motrin for use by children has not been established. It is not known whether ibuprofen is harmful to an unborn baby.


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Bayer. Aspirin Product Information.

Pfizer Consumer Healthcare. Advil Product Information.

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