Ativan vs. Valium

• Are Valium and Ativan the Same Thing?
• What Are Possible Side Effects of Ativan?
• What Are Possible Side Effects of Valium?
• What is Ativan?
• What is Valium?
• What Drugs Interact with Ativan?
• What Drugs Interact with Valium?
• How Should Ativan Be Taken?
• How Should Valium Be Taken?

Ativan (lorazepam) and Valium (diazepam) are both used to treat anxiety disorders and other psychiatric disorders.

Both drugs are members of the benzodiazapine family of medications. According to the current understanding of neuroscience, anxiety disorders are a result of excess neural activity in the brain. Benzodiazapines like Ativan and Valium suppress the excess nerve activity by affecting a specific neurotransmitter (messenger chemical) called gamma-aminobutyric acid (GABA).

Ativan and Valium, like other benzodiazapines, are addictive and people taking them may experiences withdrawal symptoms if they stop treatment abruptly.

The central difference between lorazepam and diazepam is lorazepam leaves a person's system more quickly, reducing the chance of toxicity or side effects. Side effects of both Ativan and Valium, aside from potential addiction, include drowsiness, fatigue, depression, unsteadiness, and memory problems.

Ativan also has fewer unfavorable interactions with other medications when compared to Valium. Both drugs, however, can cause dangerous increased sedation when consumed with alcohol.

Most adverse reactions to benzodiazepines, including CNS effects and \respiratory depression, are dose dependent, with more severe effects occurring with high doses.

• Drowsiness
• Dizziness
• Tiredness
• Muscle weakness
• Headache
• Blurred vision
• Sleep problems (insomnia)
• Loss of balance or coordination
• Forgetfulness or amnesia
• Difficulty concentrating
• Nausea
• Vomiting
• Constipation
• Changes in appetite
• Skin rash

Side effects of Valium include

• drowsiness,
• tired feeling,
• dizziness,
• spinning sensation,
• fatigue,
• constipation,
• ataxia (loss of balance),
• memory problems,
• restlessness,
• irritability,
• muscle weakness,
• nausea,
• drooling,
• dry mouth,
• slurred speech,
• blurred or double vision,
• skin rash,
• itching, or
• loss of interest in sex.

Ativan (lorazepam) is indicated for the management of anxiety disorders or for the short-term relief of the symptoms of anxiety or anxiety associated with depressive symptoms. Anxiety or tension associated with the stress of everyday life usually does not require treatment with an anxiolytic.

Valium is indicated for the management of anxiety disorders or for the short-term relief of the symptoms of anxiety. Anxiety or tension associated with the stress of everyday life usually does not require treatment with an anxiolytic.

In acute alcohol withdrawal, Valium may be useful in the symptomatic reliefc of acute agitation, tremor, impending or acute delirium tremens and hallucinosis.

Ativan produces increased central nervous system (CNS) depressant effects when administered with other CNS depressants such as alcohol, barbiturates, antipsychotics, sedative/hypnotics, anxiolytics, antidepressants, narcotic analgesics, sedative antihistamines, anticonvulsants,and anesthetics

The use of clozapine and lorazepam may produce marked sedation, excessive salivation, hypotension, ataxia, delirium, and respiratory arrest.

Centrally Acting Agents

If Valium is to be combined with other centrally acting agents, careful consideration should be given to the pharmacology of the agents employed particularly with compounds that may potentiate or be potentiated by the action of Valium, such as phenothiazines, antipsychotics, anxiolytics/sedatives, hypnotics, anticonvulsants, narcotic analgesics, anesthetics, sedative antihistamines, narcotics, barbiturates, MAO inhibitors and other antidepressants.

Alcohol

Concomitant use with alcohol is not recommended due to enhancement of the sedative effect.

Antacids

Diazepam peak concentrations are 30% lower when antacids are administered concurrently. However, there is no effect on the extent of absorption. The lower peak concentrations appear due to a slower rate of absorption, with the time required to achieve peak concentrations on average 20 - 25 minutes greater in the presence of antacids. However, this difference was not statistically significant.

Ativan (lorazepam) is administered orally. For optimal results, dose, frequency of administration, and duration of therapy should be individualized according to patient response. To facilitate this, 0.5 mg, 1 mg, and 2 mg tablets are available.

The usual range is 2 to 6 mg/day given in divided doses, the largest dose being taken before bedtime, but the daily dosage may vary from 1 to 10 mg/day.

For anxiety, most patients require an initial dose of 2 to 3 mg/day given two or three times a day.

For insomnia due to anxiety or transient situational stress, a single daily dose of 2 to 4 mg may be given, usually at bedtime.

For elderly or debilitated patients, an initial dosage of 1 to 2 mg/day in divided doses is recommended, to be adjusted as needed and tolerated.

The dosage of Ativan (lorazepam) should be increased gradually when needed to help avoid adverse effects. When higher dosage is indicated, the evening dose should be increased before the daytime doses.

Take Valium exactly as your healthcare provider tells you to take it. Your healthcare provider will tell you how much Valium to take and when to take it.

Talk to your healthcare provider about slowly stopping Valium to avoid withdrawal symptoms.

If you take too much Valium, call your healthcare provider or go to the nearest hospital emergency room right away.