Medical Editor: John P. Cunha, DO, FACOEP
What Is Atridox?
What Are Side Effects of Atridox?
Common side effects of Atridox include:
- gum discomfort,
- pressure sensitivity,
- periodontal problems,
- gum inflammation,
- upset stomach, and
Tell your dentist if you have unlikely but serious side effects of Atridox including:
- tooth loosening,
- jaw pain, or
Dosage for Atridox
Talk to your doctor or dentist about your individual dosage recommendation.
What Drugs, Substances, or Supplements Interact with Atridox?
Rifampin and rifabutin may interact with Atridox. Tell your doctor or dentist all medications you take. Atridox can cause tooth discoloration if used in children and infants during tooth development.
Atridox During Pregnancy or Breastfeeding
Do not use Atridox if you are pregnant or breastfeeding.
Our Atridox (doxycycline hyclate) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
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Remember that your dentist has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
Tell your dentist immediately if any of these unlikely but serious side effects occur: tooth loosening, jaw pain, sunburn.
A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
In the US -
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
Read the entire patient information overview for Atridox (Doxycycline Hyclate)
In clinical trials involving a total of 1436 patients, adverse experiences from all causalities were monitored across treatment groups.
In the Circulatory System category, 10 subjects (1.6%) in the ATRIDOX (doxycycline hyclate) ® group were reported as having “unspecified essential hypertension.” Only 1 subject (0.2%) in the Vehicle group, and none in the Scaling and Root Planing or Oral Hygiene groups were reported to have “unspecified essential hypertension.” In all cases, the event occurred anywhere from 13 to 134 days post treatment. There is no known association of oral administration of doxycycline with essential hypertension.
Two patients in the polymer vehicle group and none in the ATRIDOX (doxycycline hyclate) ® group (0.2% for both groups combined) reported adverse events consistent with a localized allergic response.
Sex, age, race and smoking status did not appear to be correlated with adverse events.
The following table lists the incidence of treatment-emergent adverse events from all causalities, across all treatment groups, occurring in ≥ 1% of the entire study population.
|Body System Verbatim Terms||Doxycycline
|High blood pressure||1.60%||0.20%||0.00%||0.00%|
|Gum discomfort, pain or soreness; loss of attachment; increased pocket depth||18.10%||23.00%||20.10%||21.00%|
|Toothache, pressure sensitivity||14.30%||14.30%||10.30%||18.10%|
|Periodontal abscess, exudate, infection, drainage, extreme mobility, suppuration||9.90%||10.90%||10.30%||8.60%|
|Thermal tooth sensitivity||7.70%||8.50%||4.40%||6.70%|
|Gum inflammation, swelling, sensitivity||4.10%||5.80%||5.40%||5.70%|
|Soft tissue erythema, sore mouth, unspecified pain||4.30%||5.30%||2.70%||6.20%|
|Indigestion, upset stomach, stomachache||3.60%||4.10%||2.90%||3.80%|
|Tooth mobility, bone loss||2.00%||0.70%||0.50%||2.40%|
|Periapical abscess, lesion||1.50%||1.90%||1.00%||0.50%|
|Aphthous ulcer, canker sores||0.70%||1.70%||1.00%||1.40%|
|Endodontic abscess, pulpitis||1.50%||1.50%||0.00%||0.50%|
|Premenstrual tension syndrome||4.40%||3.10%||2.50%||3.30%|
|Body aches, soreness||1.60%||1.20%||1.50%||1.40%|
|Nausea and vomiting||1.80%||0.70%||2.50%||0.50%|
|Injury & Poisoning|
|Pain in arms or legs||1.50%||2.20%||2.00%||2.40%|
|Lower back pain||1.60%||1.70%||0.50%||2.90%|
|Stuffy head, post nasal drip, congestion||5.60%||7.70%||2.90%||4.80%|
|Skin & Subcutaneous Tissue|
|Skin infection or inflammation||1.30%||1.00%||1.00%||1.00%|
Read the entire FDA prescribing information for Atridox (Doxycycline Hyclate)
© Atridox Patient Information is supplied by Cerner Multum, Inc. and Atridox Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.