Atripla vs. Triumeq

Are Triumeq and Atripla the Same Thing?

Atripla (efavirenz/emtricitabine/tenofovir disoproxil fumarate) and Triumeq (abacavir, dolutegravir, and lamivudine) are combinations of antiviral medication used to treat HIV, which causes acquired immunodeficiency syndrome (AIDS).

Side effects of Atripla and Triumeq that are similar include dizziness, trouble sleeping (insomnia), nightmares or abnormal dreams, tiredness/fatigue, headache, nausea, vomiting, diarrhea, and changes in the shape or location of body fat (especially in your arms, legs, face, neck, breasts, and waist).

Side effects of Atripla that are different from Triumeq include drowsiness, trouble concentrating, gas, upset stomach, and skin discoloration (such as small spots/freckles, darkening of the palms of the hands/soles of the feet).

Side effects of Triumeq that are different from Atripla include fever, loss of appetite, low energy, numbness and tingling, hypersensitivity reactions (fever, rash, shortness of breath, cough, or sore throat), joint pain or swelling, muscle pain, swelling of extremities, depression, and spinning sensation (vertigo).

Both Atripla and Triumeq may interact with seizure medicines, methadone, other antiretrovirals, and other HIV medicines.

Atripla may also interact with sertraline, blood thinners, cholesterol medications, antibiotics, and calcium channel blockers.

Triumeq may also interact with St. John's wort, dofetilide, cation-containing antacids or laxatives, sucralfate, buffered medications, oral calcium and iron supplements (including multivitamins containing calcium or iron), metformin, and rifampin.

SLIDESHOW

A Timeline of the HIV/AIDS Pandemic See Slideshow

What Are Possible Side Effects of Atripla?

Common side effects of Atripla include:

  • dizziness,
  • trouble sleeping,
  • drowsiness,
  • unusual dreams, and
  • trouble concentrating.

Side effects may begin 1-2 days after starting Atripla and usually go away in 2-4 weeks. Other side effects of Atripla include:

  • tiredness,
  • headache,
  • nausea,
  • vomiting,
  • gas,
  • upset stomach,
  • diarrhea, and
  • skin discoloration (such as small spots/freckles, darkening of the palms of the hands/soles of the feet), and
  • changes in the shape or location of body fat (especially in your arms, legs, face, neck, breasts, and waist).

Tell your doctor if you have serious side effects of Atripla including:

  • unexplained weight loss,
  • persistent muscle aches or weakness,
  • joint pain,
  • numbness or tingling of the hands/feet/arms/legs,
  • severe tiredness,
  • vision changes,
  • severe or persistent headaches,
  • signs of infection (such as fever, chills, trouble breathing, cough, non-healing skin sores),
  • signs of an overactive thyroid (such as irritability, nervousness, heat intolerance, fast/pounding/irregular heartbeat, bulging eyes, unusual growth in the neck or thyroid known as a goiter), or
  • signs of a certain nerve problem known as Guillain-Barre Syndrome (such as difficulty breathing/swallowing/moving your eyes, drooping face, paralysis, slurred speech).

What Are Possible Side Effects of Triumeq?

Common side effects of Triumeq include:

  • insomnia,
  • headache,
  • fatigue,
  • diarrhea,
  • nausea,
  • vomiting,
  • fever,
  • loss of appetite,
  • low energy,
  • nightmares or abnormal dreams,
  • abnormal body fat distribution,
  • numbness and tingling,
  • hypersensitivity reactions (fever, rash, shortness of breath, cough, or sore throat),
  • joint pain or swelling,
  • muscle pain,
  • extremity swelling,
  • depression,
  • dizziness, and
  • spinning sensation (vertigo).

What Is Atripla?

Atripla (efavirenz/emtricitabine/tenofovir disoproxil fumarate) is an antiviral medication that treats HIV, which causes acquired immunodeficiency syndrome (AIDS). Atripla is not a cure for HIV or AIDS.

What Is Triumeq?

Triumeq (abacavir, dolutegravir, and lamivudine) is a combination of an integrase strand transfer inhibitor (INSTI) and two nucleoside analogues used to treat human immunodeficiency virus type 1 (HIV1) infection.

QUESTION

What is HIV? See Answer

What Drugs Interact With Atripla?

Atripla (efavirenz, lamivudine and tenofovir disoproxil fumarate) is a three-drug combination of a non-nucleoside reverse transcriptase inhibitor, and two nucleo(t)side reverse transcriptase inhibitors indicated as a complete regimen for the treatment of human immunodeficiency virus type 1 (HIV-1) infection in adult and pediatric patients weighing at least 40 kg.

What Drugs Interact With Triumeq?

Triumeq may interact with dofetilide and other drugs. Tell your doctor all medications and supplements you use.

How Should Atripla Be Taken?

The adult dose of Atripla is one tablet once daily taken orally on an empty stomach. Dosing at bedtime may improve the tolerability of nervous system symptoms.

How Should Triumeq Be Taken?

The adult dose of Triumeq is one tablet daily.

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References
Gilead. Atripla Prescribing Information.

https://www.atripla.com/

ViiV. Triumeq Product Information.

https://viivhealthcare.com/en-gb/our-medicines/triumeq/

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