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Autoplex-T

Last reviewed on RxList: 1/13/2009
Autoplex-T Side Effects Center

Medical Editor: John P. Cunha, DO, FACOEP

Last reviewed on RxList 6/13/2016

Autoplex T (anti-inhibitor coagulant complex, heat treated) is made from proteins normally found in human blood that allow the blood to clot and is used to treat or prevent bleeding in people with hemophilia A or B and Factor VIII inhibitors. Common side effects of Autoplex T include:

  • fever
  • chills
  • pain around the IV needle
  • numbness or tingling (especially in your face)
  • changes in blood pressure or heart rate
  • headache
  • flushing

Tell your doctor if you have serious side effects of Autoplex T such as:

The recommended dosage range of Autoplex T is 25 to 100 Hyland Factor VIII Correctional Units per kg of body weight, depending upon the severity of hemorrhage. Autoplex T may interact with aminocaproic acid, desmopressin, or tranexamic acid. Tell your doctor all medications and supplements you use. It is unknown if Autoplex T will harm a fetus. Tell your doctor if you are pregnant or plan to become pregnant while using this medication. It is unknown if this drug passes into breast milk or if it could harm a nursing baby. Consult your doctor before breastfeeding.

Our Autoplex T (anti-inhibitor coagulant complex, heat treated) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

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Autoplex-T Consumer Information

Get emergency medical help if you have signs of an allergic reaction: hives; wheezing, difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor or seek emergency medical help right away if you have:

  • bruising, swelling, or pain around a joint;
  • heart attack symptoms--chest pain or pressure, pain spreading to your jaw or shoulder, nausea, sweating;
  • low red blood cells (anemia)--pale skin, feeling light-headed or short of breath, rapid heart rate, trouble concentrating;
  • signs of a stroke--sudden numbness or weakness (especially on one side of the body), sudden severe headache, slurred speech, problems with vision or balance;
  • signs of a blood clot in the lung--chest pain, sudden cough, wheezing, rapid breathing, coughing up blood or;
  • signs of a blood clot in your leg--pain, swelling, warmth, or redness in one or both legs.

Common side effects may include:

  • anemia;
  • nausea, vomiting, diarrhea;
  • bruising;
  • altered sense of taste; or
  • a positive hepatitis B antibody test.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Read the entire detailed patient monograph for Autoplex-T (Anti-Inhibitor Coagulant Complex, Heat Treated)

QUESTION

What is hemophilia? See Answer
Autoplex-T Professional Information

SIDE EFFECTS

As with other plasma preparations, reactions manifested by fever, chills or indications of protein sensitivity may be observed with the administration of Autoplex® T, Anti-Inhibitor Coagulant Complex, Heat Treated. Signs and/or symptoms of high prekallikrein activity, such as changes in blood pressure or pulse rate may also be observed. It is advisable that appropriate medications be available for the treatment of acute allergic reactions or acute vasoactive reactions, should they occur.

A rate of infusion that is too rapid may cause headache, flushing, and changes in pulse rate and blood pressure. In such instances, stopping the infusion allows the symptoms to disappear promptly. With all but the most reactive individuals, infusion may be resumed at a slower rate.

Read the entire FDA prescribing information for Autoplex-T (Anti-Inhibitor Coagulant Complex, Heat Treated)

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© Autoplex-T Patient Information is supplied by Cerner Multum, Inc. and Autoplex-T Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.

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