Medical Editor: John P. Cunha, DO, FACOEP Last updated on RxList: 12/2/2021
Azasite Side Effects Center

Medical Editor: John P. Cunha, DO, FACOEP

What Is Azasite?

Azasite (azithromycin ophthalmic solution) is a semi-synthetic macrolide antibiotic used for the treatment of bacterial conjunctivitis.

What Are Side Effects of Azasite?

Common side effects of Azasite include:

Dosage for Azasite

The recommended regimen of Azasite is 1 drop twice daily for the first two days and then 1 drop once daily for the next five days.

Azasite During Pregnancy or Breastfeeding

There are no adequate studies of Azasite in pregnant women and it is not known whether Azasite is excreted in breast milk. Only use Azasite in pregnant or nursing mothers when absolutely necessary.

Additional Information

Our Azasite Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


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Azasite Consumer Information

Stop using this medicine and get emergency medical help if you have signs of an allergic reaction (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling).

Call your doctor at once if you have:

  • drainage or crusting of your eye;
  • severe burning, stinging, itching, or other irritation after using the eye drops;
  • feeling like something is in your eye;
  • changes to the surface of your eye;
  • eye pain or swelling;
  • eyelid irritation; or
  • any signs of a new infection.

Common side effects may include:

  • eye irritation;
  • dry or itchy eyes;
  • blurred vision;
  • stuffy nose; or
  • changes in your sense of taste.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Read the entire detailed patient monograph for Azasite (Azithromycin Ophthalmic Solution)


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Azasite Professional Information


Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in one clinical trial of a drug cannot be directly compared with the rates in the clinical trials of the same or another drug and may not reflect the rates observed in practice.

The data described below reflect exposure to AzaSite in 698 patients. The population was between 1 and 87 years old with clinical signs and symptoms of bacterial conjunctivitis. The most frequently reported ocular adverse reaction reported in patients receiving AzaSite was eye irritation. This reaction occurred in approximately 1-2% of patients. Other adverse reactions associated with the use of AzaSite were reported in less than 1% of patients and included ocular reactions (blurred vision, burning, stinging and irritation upon instillation, contact dermatitis, corneal erosion, dry eye, eye pain, itching, ocular discharge, punctate keratitis, visual acuity reduction) and non-ocular reactions (dysgeusia, facial swelling, hives, nasal congestion, periocular swelling, rash, sinusitis, urticaria).

Read the entire FDA prescribing information for Azasite (Azithromycin Ophthalmic Solution)

© Azasite Patient Information is supplied by Cerner Multum, Inc. and Azasite Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.

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