- Are Baclofen and Antabuse the Same Thing?
- What Are Possible Side Effects of Baclofen?
- What Are Possible Side Effects of Antabuse?
- What Is Baclofen?
- What Is Antabuse?
- What Drugs Interact with Baclofen?
- What Drugs Interact with Antabuse?
- How Should Baclofen Be Taken?
- How Should Antabuse Be Taken?
Are Baclofen and Antabuse the Same Thing?
Baclofen is used off-label to treat alcohol addiction. Baclofen is primarily used for treating spasm of skeletal muscles, muscle clonus, rigidity, and pain caused by multiple sclerosis. Baclofen is also injected into the spinal cord to treat severe spasticity, spinal cord injuries, and other spinal cord diseases.
Brand names for baclofen include Lioresal and Gablofen.
Side effects of baclofen that are different from Antabuse include weakness, dizziness, seizures, nausea, vomiting, low blood pressure, constipation, confusion, respiratory depression, trouble sleeping (insomnia), and increased urinary frequency or urinary retention.
Both baclofen and Antabuse may interact with alcohol and other drugs that make you sleepy or slow your breathing (sleeping pills, narcotics, prescription cough medicines, muscle relaxers, or medicines for anxiety, depression, or seizures).
Abrupt discontinuation of baclofen may cause withdrawal symptoms including seizures and hallucinations, high fever, rebound spasticity, muscle rigidity, and rhabdomyolysis (muscle breakdown and wasting).
Brand names for baclofen include Gablofen and Lioresal.
What Are Possible Side Effects of Baclofen?
Common side effects of Baclofen include:
- Muscle weakness
- Blurred vision
- Sleep problems (insomnia)
- Loss of balance or coordination
- Forgetfulness or amnesia
- Difficulty concentrating
- Changes in appetite
- Skin rash
What Are Possible Side Effects of Antabuse?
Common side effects of Antabuse include:
- metallic or garlic-like taste in the mouth,
- skin rash or acne,
- impotence, and
- swollen or sore tongue.
Tell your doctor if you have a unlikely but serious side effects of Antabuse including:
- vision changes,
- numbness or tingling of arms and legs,
- muscle weakness,
- mental/mood changes (e.g., agitation, extreme excitement/confusion), or
What Is Baclofen?
Baclofen (lorazepam) is indicated for the management of anxiety disorders or for the short-term relief of the symptoms of anxiety or anxiety associated with depressive symptoms.
What Is Antabuse?
What Drugs Interact With Baclofen?
Benzodiazepines like Baclofen produce increased CNS (central nervous system) depressant effects when administered with other CNS depressants such as alcohol, barbiturates, antipsychotics, sedative/hypnotics, anxiolytics, antidepressants, narcotic analgesics, sedative antihistamines, anticonvulsants, and anesthetics.
What Drugs Interact With Antabuse?
Antabuse may interact with isoniazid, monoamine oxidase inhibitors (MAOIs), benzodiazepines, tricyclic antidepressants, warfarin, metronidazole, theophylline, phenytoin, or lithium. Tell your doctor all medications you are taking. During pregnancy, Antabuse should be used only when prescribed.
How Should Baclofen Be Taken?
How Should Antabuse Be Taken?
In the first phase of treatment, a maximum of 500 mg of Antabuse daily is given in a single dose for one to two weeks. The average maintenance dose of Antabuse is 250 mg daily (range, 125 to 500 mg), not to exceed 500 mg daily. Do not drink alcohol and avoid all alcohol-containing products (e.g., cough and cold syrups, mouthwash, or foods containing alcohol) while taking this medication.
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DailyMed. Antabuse Product Information.
Novartis. Baclofen Product Information.